SSRIs Flashcards
Citalopram
Celexa
excitalopram
Lexapro
fluoxetine
Prozac (CR once weekly - 90mg)
paroxetine
Paxil (once daily CR)
sertraline
Zoloft
SSRI indications
depression, GAD, hot flashes (off label), PTSD, OCD, eating disorders
Adverse effects
nausea/GI, decreased libido, headache, dry mouth, sweating
Pearls
paroxitine has the highest risk of weight gain, sexual dysfunction and pregnancy risk
Drug interactions
MAOIs (serotonin syndrome), SNRIs, NSAIDs (bleeding), Ondansatron (serotonin antagonist)
Warnings
suicidal thoughts/behavior in those with major psychiatric disorders
Counseling
Takes 4-6 weeks to see an effect, need to take 6-9 months after beginning relief of symptoms. Do not stop abruptly, stay hydrated (risk of suicide!!)