NSAIDS

Question 1

Celebrex

Answer 1

celecoxib - capsule

Question 2

ibuprofen

Answer 2

Motrin, Advil - capsule, tablet, liquid

Question 3

Naprosyn, Aleve

Answer 3

tablet, capsules, liquid

Question 4

meloxicam

Answer 4

tablet and liquid - Mobic

Question 5

dicofenac

Answer 5

Voltaren (tablet, gel) and Flector (patch) - tablets come in IR and ER

Question 6

COX-I

Answer 6

good, produced in most tissues

Question 7

COX-II

Answer 7

bad, produced in the pressence of inflammation and tissue damage

Question 8

COX-I inhibition

Answer 8

greater risk of GI issues

Question 9

COX-II inhibition

Answer 9

greater risk of cardiovascular issues

Question 10

celecoxib is selective to

Answer 10

COX-II

Question 11

Indications

Answer 11

pain, dysmenorrhea, fever (aleve, advil), joint pain

Question 12

Adverse effects

Answer 12

GI, bleeding, edema, increased blood pressure, kidney damage, tinnitus

Question 13

Drug interactions

Answer 13

anticoagulants, aspirin, ACE-I and ARB, corticosteroids, sulfonyureas, SSRIs

Question 14

Box warning

Answer 14

cardiovascular events, gastrointestinal

Question 15

precautions - populations

Answer 15

cardiac diseases, elderly patients, kidney disease, HTN, gastric disease

Question 16

When should aspirin be taken if planning to take NSAID?

Answer 16

30 minutes before

Question 17

Ibuprofen pearls

Answer 17

max OTC 1200, Rx 3200 - can be used in children 6 months and older