Miscellaneous Antidepressants Flashcards
amitriptyline
Elavil, tricyclic antidepressant
bupropion
Wellbutrin (depression), Zyban (smoking) - monocyclic. available IR/SR and ER (12 and 24 hours)
mirtazapine
Remeron, alpha 2 antagonist
trazodone
Desyrel, antidepressant
amitriptyline indications
depression - insomnia and neuropathic pain off label
amitriptyline adverse effects
hypotension, cardiovascular risk, anticholinergic, sedation
Buproprion does not effect
serotonin or monoamine oxidase
Bupropion indications
depression, SAD, smoking
Adverse effects - Wellbutrin
weight loss, dry mouth, insomnia, seizures
Wellbutrin interactions
alcohol, St. John’s Wort
Counseling for Wellbutrin
may see tablet in stool for ER preparation, take at same time each day - for Zyban, need 8 hours between doses
Mirtazapine indications
Depression, OCD, PTSD
Mirtazapine adverse effects
dry mouth, increased appetite, cholesterol, constipation
Which misc is available as orally disintegrating tablet?
mirtazepine - also cannot be stored once removed from blister pack
Pearls for mirtazepine
higher doses may be less sedating
Trazodone is available as
IR and ER
Trazodone indications
depression, insomnia
Trazodone adverse effects
constipation, sedation, dizziness, possible priapism
Trazodone interactions
medications that affect serotonin, CNS depressants
