Miscellaneous Antidepressants Flashcards
amitriptyline
Elavil, tricyclic antidepressant
bupropion
Wellbutrin (depression), Zyban (smoking) - monocyclic. available IR/SR and ER (12 and 24 hours)
mirtazapine
Remeron, alpha 2 antagonist
trazodone
Desyrel, antidepressant
amitriptyline indications
depression - insomnia and neuropathic pain off label
amitriptyline adverse effects
hypotension, cardiovascular risk, anticholinergic, sedation
Buproprion does not effect
serotonin or monoamine oxidase
Bupropion indications
depression, SAD, smoking
Adverse effects - Wellbutrin
weight loss, dry mouth, insomnia, seizures
Wellbutrin interactions
alcohol, St. John’s Wort
Counseling for Wellbutrin
may see tablet in stool for ER preparation, take at same time each day - for Zyban, need 8 hours between doses
Mirtazapine indications
Depression, OCD, PTSD
Mirtazapine adverse effects
dry mouth, increased appetite, cholesterol, constipation
Which misc is available as orally disintegrating tablet?
mirtazepine - also cannot be stored once removed from blister pack
Pearls for mirtazepine
higher doses may be less sedating