SSRIs

Question 1

Fluoxetine/Prozac

Answer 1

dosing-
start- 20mg/day (equivalent- 90mg 1x/week pill)
max dose 80mg/day

ADRs
sexual dysfunction
possible but not expected weight gain
GI- NV that tends to last 2 weeks after starting the med
CNS (insomnia, sedation, agitation, tremors, headache, dizziness)
may induce mania
Can cause hyponatremia (dizziness, clumsiness)

Takes 4 to 8 weeks for full efficacy

Question 2

Sertraline/Zoloft

Answer 2

Take in the evening- tends to make people sleepy
Should feel less depression and anxiety by week 3
First 2 weeks- may have increased anxiety and N/V
Long term- can cause wt gain and sexual dysfunction

SSS- stomach (nausea, vomiting), sexual dysfunction, very rare serotonin syndrome

Takes 4 weeks to see around 20% improvement in symptoms
Takes 8 weeks to see a full effect
ADRs
Sexual ADRs
GI- nausea, diarrhea, constipation, dry mouth
CNS- insomnia or sedation, agitation, tremors, HA, dizziness
Autonomic- sweating
SIADH
Can cause hyponatremia

Question 3

Escitalopram/Lexapro

Answer 3

Wakes people up
Fast onset of action
Good for panic attacks
Good for PTSD
Works on both insomnia and hypersomnia
Good for anxiety
Can decrease appetite

ADRs
Sexual ADRs
GI ADRs (nausea, diarrhea, dry mouth, constipation)
CNS ADRs (agitation, tremors, headache, dizziness, insomnia, sedation)

Question 4

Paroxetine/Paxil

Answer 4

Good for anxiety
Good for depression
Good for insomnia

Sexual ADRs
Can cause weight gain
Can decrease appetite
GI ADRs (dry mouth, nausea, constipation, diarrhea)
CNS ADRs (headache, tremors, dizziness, insomnia or hypersomnia, agitation)

Question 5

Citalopram/celexa

Answer 5

GI- constipation, reduced appetite, nausea, dry mouth, diarrhea
Neuro- sedation, dizziness, blurry vision, headache, tremors, insomnia, agitation
Sexual dysfunction