Antipsychotics And Mood Stabilizers

Question 1

GEODON/ZIPRASIDONE

Answer 1

Must take with 500 calorie meal to be effective
Sedating- take at night

Question 2

Aripiprazole /Abilify

Answer 2

ADRs
Can be activating
Sedating for some people
Restlessness (15% of pts)
TD- involuntary movements

Question 3

Brexipiprazole /rexulti

Answer 3

ADRs
Restlessness
TD
weight gain
sedation

Question 4

Quetiapine/seroquel

Answer 4

ADRs
Most people take it only at night
Weight gain
TD
Metabolic effects

Question 5

trifluoperazine/Stelazine

Answer 5

can cause allergic reactions for people with asthma (contains sulfites)

ADRs
risk of TD
sedation (usually transient)/dizziness
akathisia
priapism and other sexual side effects
galactorrhea

Question 6

Lurasidone/Latuda

Answer 6

Must take with at least 350 calories of food
Can be sedating- take at night
WEIGHT NEUTRAL
Low on metabolic side effects (glucose and lipid changes)

ADRs-
Sedation
Restlessness/akathisia
Can raise PROLACTIN
TD
Metabolic side effects

Question 7

Olanzapine/Zyprexa

Answer 7

ADRs
Drowsiness
Weight gain
Metabolic ADRs
TD
Postural hypotension
(At high doses- can cause breast tissue changes)
Can reduce ability to manage body temperature- be careful when outside, make sure you do not overheat

Smoking cigarettes can lower blood level of the medication

TAPER OFF SLOWLY to avoid rebound psychosis

Question 8

Risperidone/Risperdal

Answer 8

ADRs-
TD
elevated prolactin- nipple discharge, nipple soreness, enlarged breast tissue
metabolic ADRs
sleep changes (insomnia or sedation)
dizziness
anxiety

Question 9

Fluphenazine/Prolixin

Answer 9

Do not take if you have an aspirin allergy
Stop the med if ANC<1000/cubic mm
ADRs-
TD
sexual side effects (priapism)
Restlessness/akathisia
Elevated prolactin- galactorrhea/amenorrhea

Question 10

Trileptal/oxcarbazepine

Answer 10

Use a second form of contraception- it reduces the efficacy of hormonal birth control
May cause a rash, which leads to SJS if medication is not stopped
Monitor for clumsiness and dizziness- signs of hyponatremia

Question 11

Lumateperone/Caplyta

Answer 11

Low on EPS and akathisia
Low on metabolic ADRs and weight gain
Good for- aggression
Positive and negative symptoms
Cognitive symptoms
Unstable mood
ADRs
Sedation
Dry mouth
Constipation
TD