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REUMA > SS > Flashcards

SS Flashcards

1
Q

Qué clasificacion de Sj tiene mayor malignidad?

A

Primaria

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2
Q

Epidemio

A

40a
Mujeres

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3
Q

Genes asociados

A

HLA-B8, DR3, Dw52

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4
Q

Factores que influyen en la reactividad autoinmune

A

Vira
Hormonal (mujeres)
Genes HLAB8, DR3, Dw52
Psicológicos

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5
Q

Factor que influye mas en la reactividad inmune?

A

Viral

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6
Q

Fisiopatología

A

Generacion citocinas
Antígenos = estimulacion = DAÑO
** Retroalimentacion

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7
Q

Sello característico del SS (cel que se afecta más)

A

Linfocito B

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8
Q

Labs en un px típico

A

VSG +
IgG
Anemia normo-normo
ANA anti-Ro/LA
C4 baja

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9
Q

Tiempo mínimo de evolucion de la enf

A

3 meses

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10
Q

Sello característico en antigenos?

A

ANA + con patron moteado
Anti Ro +

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11
Q

Indica riesgo de neoplasia

A

C4 bajo

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12
Q

Def de Parptiditis

A

Inflamacion transitoria x obstruccion en caniculos

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13
Q

Miopatía inflamatoria comun

A

Miosistis proximal de musc grandes: cintura, escapula, pelvis

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14
Q

DX ocular para manifestaciones oculares objetivas

A

Schirmers test

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15
Q

TX sintomatico

A

lubricantes y dirigido a manifestaciones

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16
Q

TX de mantenimiento

A

Rituximab

17
Q

Los anticuerpos antiRO/La + un focus >= a 1 tienen…

A

mayor rendimiento dx

REUMA (9 decks)

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