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BACTE (CHAPTER 16) > Spore-forming, Nonbranching Catalase Positve > Flashcards

Spore-forming, Nonbranching Catalase Positve Flashcards

1
Q

Gram +, catalase +, aerobic/facultative anaerobes

A

Bacillus

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2
Q

Bacillus can be confused with ___

A

Clostridium spp.

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3
Q

Most medical relevant group of bacillus.

A

Bacillus cervus group
-B. anthracis
-B. cereus
-B. thuringiensis
-B. mycoides

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4
Q

Most important member of B. cereus group.

A

B. anthracis

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5
Q

Vrulence factors of B. anthracis

A

-Glutamic acid capsule
-anthrax toxin (three-component protein exotoxins) lethal

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6
Q

Virulence factors of B. anthracis that code the genes for toxins carried on plasmid

A

Anthrax toxins

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7
Q

This virulence factors of B. anthracis is resistant to hydrolysis by proteolytic enzymes.

A

Glutamic acid capsule

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8
Q

3 proteins of Anthrax.

A

Protective antigen (PA)
Edema factor (EF)
Lethal factor (LF)

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9
Q

T or F
in anthrax toxin protein. Each of which individually is nontoxic but which together act synergistically to cause effect.

A

True

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10
Q

Protein of anthrax toxin that bind molecules and protect EF and LF

A

Protective antigen

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11
Q

Among the 3 proteins of anthrax toxins, which one is adenylate catalase?

A

Edema factor (EF)

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12
Q

Protease that kills host cells by disrupting the transduction of extracellular regulatory signals

A

Lethal factor

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13
Q

EF +LF =

A

Edema

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14
Q

LF+PA

A

Death

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15
Q

Common disease in livestock.

A

Anthrax

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16
Q

How does the anthrax spread?

A

When animals eat plants that contaminated with spore.

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17
Q

T or F
Human are infected primarily as a result of accidental or occupational exposure to animals or animals product.

A

True

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18
Q

Other name of Anthrax disease

A

Woolsorter’s disease
Ragpicker’s disease

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19
Q

3 form of anthrax

A

Cutaneous anthrax
Inhalation anthrax
Gastrointestinal anthrax

20
Q

It occurs when wounds are contaminated with anthrax spores acquired through skin, cuts, abrasions, insect bites.

A

Cutaneous anthrax

21
Q

The majority of anthrax cases

A

Cutaneous anthrax

22
Q

Cutaneous anthrax infection starts with ___.

A

Small pimple /papule

23
Q

Cutaneous anthrax
A ring of vesicles develops, and the vesicle _______ to form ___.

A

Coalase
Erythematous ring

24
Q

What do you call the dark area in the center of a ring that cause ulcers and dryness.

A

Eschar/black eschar

25
Q

Forming depresse black necrotic central called.

A

Eschar/black eschar

26
Q

Form of anthrax that is known as ___.

A

Woolsorter’s disease

27
Q

Acquired when sporees are inhaled into pulmonary parenchyma

A

Inhalation anthrax

28
Q

Most deadly type of anthrax.

A

Inhalation anthrax

29
Q

Bioterrorism agent

A

Inhalation anthrax

30
Q

Occurs when the spores are inoculated into lesion on the intestinal mucosa after ingestion of spores.

A

Gastrointestinal anthrax

31
Q

What are the symptoms of GIT anthrax?

A

Abdominal pain
Nausea
Anorexia
Vomiting
Bloody diarrhea

32
Q

It is characterized by soft tissue infection associated with skin popping or direct inject of spores in tissue

A

Injection anthrax

33
Q

Lab diagnosis
Large
Squared-ended
Gram(+)
Rod (single /chain)

A

Bacillus

34
Q

The chain of bacillus resembles ___.

A

Bamboo rods.

35
Q

In the gram stain of bacillus, the vegetative cell has a clear zone that surrounds the colony in is known as ___.

A

Capsule

36
Q

Cultural characteristics of Bacillus anthrax.

A

Nonhemolytic, large, gray, flat

37
Q

The colonies of B. anthracis is known as ___.

A

Medusa head

38
Q

T or F
The consistency of B. anthracis in agar is Tenacious consistency (beaten egg white).

A

True

39
Q

Recommend agar for B. anthracis.

A

PEA agar

40
Q

Which of the following is not the identification of B. anthracis?
A. Produce mannitol
B. Nonmotile
C. Produce lecithinase
D. Grow in high salt(7%NaCl and low pH)

A

A.

41
Q

After how many hours of incubation for the observation of B. anthracis and at what temp?

A

After 3-6 hours
At 37°C

42
Q

Type of Bacillus sp. That is responsible for food poisoning and oppurtunistic infection.

A

Bacillus cereus

43
Q

Food poisonning of B. cereus in two form.

A

Diarrheal
Emetic form

44
Q

Form of food poisoning caused by B. cereus due to ingestion of meet, poultry, vegetables, pastas.

A

Diarrheal

45
Q

Diarrheal form
-Clin. Indistinguishable from diarrheal cause by ___.

A

Clostridium perifringens

BACTE (CHAPTER 16) (4 decks)

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