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ABSITE > Spleen > Flashcards

Spleen Flashcards

1
Q

T/F Short gastrics and splenic artery are end arteries

A

True

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2
Q

T/F Splenic vein is posterior/inferior to splenic artery

A

True

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3
Q

Most common antibody in spleen

A

IgM

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4
Q

Red vs. White pulp in spleen

A

Red: filter for aged/damaged RBC’s
- Pitting: removal of abnormalities in RBC membrane
White: 15% – immunologic

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5
Q

Howell-Jolly bodies vs. Heinz bodies

A

HJ: nuclear remnants
Heniz: Hgb

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6
Q

What is tuftsin?

A

An opsonin, facilitates phagocytosis; produced in spleen

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7
Q

What is properdin

A

Activates alternate complement pathway

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8
Q

Where is accessory spleen most commonly found?

A

At hilum

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9
Q

Most common non-traumatic condition requiring splenectomy

A

ITP

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10
Q

What condition is caused by anti-platelet antibodies?

A

ITP

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11
Q

Is the spleen normal in ITP?

A

Yes

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12
Q

Should you avoid splenectomy in children < 10 years old?

A

Yes

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13
Q

Primary and secondary therapy for ITP

A

Steroid; gammaglobiulin

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14
Q

TTP

A

Loss of platelet inhibition; leads to thrombosis and infarction; profound thrombocytopenia

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15
Q

Treatment of TTP

A

Plasmapheresis

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16
Q

Most common cause of death following TTP

A

Intracerebral hemorrhage, ARF

17
Q

Highest risk of post-splenectomy sepsis syndrome

A

Hemolytic disorders or malignancy

18
Q

How old should you be before a splenectomy in a child

A

5 years old

19
Q

Should you vaccinate before or after splenectomy

A

Before (14 days before elective surgery; 14 days after emergency surgery)

20
Q

Most common congenital hemolytic anemia requiring splenectomy

A

Spherocytosis; and ccy

21
Q

Is splenectomy required in SC anemia?

A

No; spleen usually auto-infarcts

22
Q

Stage 1–>4 Hodgkin’s

A

Stage I: 1 area or 2 areas on same side as diaphragm

2: Non-contig
3. Bilateral diaphragm
4: Liver, bone, lung

23
Q

Reed-Sternberg cells

A

Seen in Hodgkin’s lymphoma

24
Q

Best/Worst prognosis in Hodgkin’s lymphoma subtypes

A

Predom (best); lymphocyte depleted – worst prognosis

25
Q

MCC of chylous ascites

A

Lymphoma

26
Q

Some causes of spontaneous splenic rupture

A

Mono, malaria, sepsis, sarcoid, leukemia, PV

27
Q

What is splenosis?

A

Splenic implants – usually related to trauma

28
Q

Most common cause of splenic artery or splenic vein thrombosis

A

Pancreatitis

29
Q

Number one splenic tumor

A

Hemangioma

30
Q

1 malignant splenic tumor, MCC of splenomegaly

A

NHL

31
Q

1 malignant non-blood cell splenic tumor

A

Angiosarcoma

32
Q

When do you resect splenic cysts?

A

> 10 cm or symptomatic

33
Q

Treatment of splenic abscess

A

Splenectomy

34
Q

Treatment of echinococcal or dermoid cyst

A

Splenectomy

35
Q

What are pappenheimer bodies?

A

Iron deposits

ABSITE (14 decks)

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