Skin, Soft Tissue Flashcards

1
Q

MCC pedicled, or anastamosed free flap necrosis

A

Venous thrombosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Tissue expansion occurs by

A

Local recruitment, thinning of dermis and epidermis, mitosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

TRAM flaps

A

Complications – flap necrosis, ventral hernia, infection, abdominal wall weakness
- Rely on superior epigastric vessesls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pressure sore stages

A

I: Erythema and pain
II: Partial skin loss with yellow debris
III: Full thickness, subcutaneous fat exposure [sharp debridement]
IV: bony cortex; muscle; adipose tissue; tendon [myocutaneous flap]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Single best factor for protecting skin from UV radiation

A

Melanin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

UV a or b is responsible for chronic sun damage

A

UVB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Risk factors for melanoma

A

Dysplastic, atypical, large congenital nevi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What syndrome results in 100% risk of malnoma

A

Familial BK mole syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

MC site of melanoma on men vs. women

A

Men: Back
Women: Legs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

From what cell layer does melanoma originate?

A

Neuroal crest cells (melanocytes) in basal layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What color melanoma is most ominous?

A

Blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Most common location for distant melanoma mets

A

Lung

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Most common mets to small bowel

A

Melanoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What stains do you use for melanoma?

A

S-100 and HMB-45 proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

< 2 vs > 2 cm melaoma

A

Excisional; incisional bx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Most aggressive type of melanoma

A

Nodular; most likely to have metastsized at time of diagnosis

17
Q

Staging of melanoma

A

CAP CT; LFTs; LDH

18
Q

Surgical margins for melanoma excision

A

In situ (0.5 cm); Thin <1mm (1 cm); Intermediate 1.1-2mm (1-2 cm); Thick >2mm (2 cm)

19
Q

When do you need to resect nodes with melanoma?

A

Clinically positive; SLNB+

20
Q

When do you perform SLNB with melanoma?

A

Clinically node negative disease and tumor > 1mm deep

21
Q

For all scalp melanomas anterior to the ear and above the lip…

A

Need to include superficial parotidectomy

22
Q

First-line CTX for metastatic melanoma

A

Dacarbazine

23
Q

T/F Il-2 and tumor vaccines can be used for systemic disease

24
Q

80% Basal Cell Ca is located…

25
Pearly appearance, rolled borders, slow and indolent growth is characteristic of what type of skin cancer
BCC
26
Pathology of basal cell carcinoma
Peripheral palisaiding of nuclei and stromal retraction
27
What size margins for basal cell carcinoma?
0.3-0.5 cm margins
28
Most aggrsesive type of basal cell carcinoma
Morpheaform type
29
Old burn scars can predispose to this kind of skin cancer
SCC
30
Margins for SCC
0.5-1cm margins
31
#1 soft tissue sarcoma
#1 malignant fibrous histiosarcoma
32
Do you do an MRI before biopsy of a soft tissue sarcoma?
Yes -- to rule out vascular, neuro or bone invasion
33
How do sarcomas spread
Through blood
34
Post-op CTX for soft tissue sarcomas
Doxorubicin
35
Chronic lymphedema can pre-dispose to
Lymphangiosarcoma
36
Syndrome a/w childhood rhabdomyosarcoma
Li-Fraimeni
37
Tuberous sclerosis is a/w which sarcoma
Angiomyolipioma
38
Most common mesenchymal tumor
Lipoma