Spirometry and Lung Compliance Flashcards
The objective of this lecture is to understand how spirometry measures basic lung functions and how these lung functions are affected by compliance.
IRV
Inspiratory Reserve Volume
TV
Tidal Volume
ERV
Expiratory Reserve Volume
RV
Residual Volume
TLC
Total Lung Capacity
IC
Inspiratory Capacity
FRC
Functional Residual Capacity
VC
Vital Capacity
FEV1
Forced Expiratory Volume in 1 second
Breath in (inspire to IRV) and then Exhale as much as possible!!!
Normal FEV1 level
4 L
Normal FVC level
5 L
Normal FVC Ratio
80%
What are common obstructive disorders?
- Asthma
- Bronchitis
- Emphysema
- COPD
- Cystic Fibrosis
- ARDS (surfactant is destroyed by neutrophil aggregation)
- Obstructive Atelectasis
What are common Restrictive Diseases?
- Pulmonary Fibrosis
2. Pulmonary Edema
FEV1 for Obstructive Disease
Very Decreased
FVC for Obstructive Disease
Normal or Slightly Decreased
FEV1/FVC Ratio for Obstructive Disease
Decreased
FEV1 for Restrictive Disease
Decreased
FVC for Restrictive Disease
Decreased
FEV1/FVC Ratio for Restrictive Disease
Normal or Increased
Obstructive Disease is defined by
Expiration being Obstructed
Restrictive Disease is defined by
Lung Inflation is being Restricted
Compliance is defined as
- Ability to yield and stretch when under a force –“Distendable”
Compliance =
The Change in Ventilation divided by the Change in Pressure
What makes Surfactant in the Alveoli?
Type 2 Alveolar Cells
Pressures will naturally flow from ______ alveoli into the _____ ones when a pressure gradient exists.
Small to Large
Surfactant ‘detergent’ permits small alveoli patency and expansion even when connected to large alveoli.
KNOW THIS
Surfactant modifies surface tension to ________.
Prevent collapse of small alveoli when connected to larger alveoli.
How does surfactant increase compliance?
Decreasing Surface Tension
Abnormally high compliance (Lung Volume is high and TPPG is lower)
Emphysema
Abnormally low compliance (Lung Volume is low and TPPG is higher)
Pulmonary Fibrosis