Spine clinical correlations Flashcards
What is Lhermitte’s sign?
- passive anterior cervical flexion elicits “electric” sensation down the spine or extremities
- implies cervical spinal cord pathology
What is Spurling’s test?
- cervical spine extension + rotation (towards affected side) + lateral flexion
- pain/”electric” feeling upon compression implies cervical nerve root pathology
- e.g. herniated disc
What is hoffmann’s sign?
- flick the patient’s middle finger
- positive= flexion-adduction of ipsilateral thumb and index finger
- implies upper motor neuron process affecting cervical spine or brain
What is the straight leg raising (SLR) test?
- also called Lasegue sign
- positive test= leg pain reproduced at 30-70 degrees
- implies lumbar nerve root pathology (L5 or S1)
What is the femoral nerve stretch test?
- patient is placed in prone position with flexed knee and examiner lifts the leg (hip extension)
- positive test= reproduction of patient’s pain in anterior thigh
- implies upper lumbar nerve root pathology (L2-L4)
What are the common symptoms of an upper motor neuron injury?
- spasticity/hypertonicity
- increased reflexes
- extensor plantar (+ babinski) response
**spinal cord injury, brain injury/stroke, myelopathy, CNS lesion
What are the common symptoms of a lower motor neuron injury?
- flaccid weakness
- loss of reflexes
- muscle wasting/atrophy
**peripheral nerve entrapment or radiculopathy (nerve root problem)
What are 2 red flags for malignancy?
- history of cancer
- unexplained weight loss
What are 5 red flags for spinal fracture?
- major trauma
- minor trauma or strenuous lifting in an older individual
- prolonged corticosteroid use
- osteoporosis
- advanced age (>70 years)
What are 4 red flags for infection?
- constitutional symptoms (fever, chills)
- recent bacterial infection (UTI, skin infection, pneumonia)
- immunosuppression
- IV drug use
What are 4 red flags for cauda equina syndrome?
- acute onset of urinary incontinence/retention
- fecal incontinence, loss of anal sphincter tone
- saddle anesthesia
- global/progressive weakness in lower limbs
Define lumbar strain
- muscle disruption from excessive stretch or tension
- pain worse with movement, better at rest
- localized muscle tenderness, reduced ROM, normal neuro exam
What makes the symptoms of a herniated disc better/worse?
- worse
- lumbar= sitting, bending, coughing/sneezing
- cervical= ROM
- better
- lumbar= standing, walking
- cervical= lying
What are the most common causes of radiculopathy?
**disc herniation (posterolateral herniation through the posterior longitudinal ligament)
- cervical= C6, C7
- lumbar= L5, S1
Describe the pathophysiology of radiculopathy
- mechanical compression
- neural ischemia/increased intraneural pressure
- edema of nerve root/DRG
- dura is mechanically sensitive
- biochemical irritation
- nucleus pulposis (inner core of the vertebral disc) contains cytokines, leukotrienes, Cox2, IL1, TNF alpha
- can cause apoptosis of DRG cells