Spinal Cord Disease - Acute & Progressive Flashcards

1
Q

IVDH type I description

A

degeneration of the nucleus pulpous leading to EXTRUSION and loss of NP function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

what are differentials for acute, progressive myelopathies

A
  1. IVDH type I
  2. discospondylitis
  3. infectious meningomyelitis
  4. non-infectious meningomyelitis (MUO/SRMA)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

IVDH type I signalment

A

breeds: chondrodystrophic dogs
age: young to middle (<4 to 6 years)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

IVDH type I pathogenesis

A
  1. early disc degeneration
  2. disc replaced with fibrocartilage
  3. chondroid metaplasia
  4. disc dehydration and mineralization
  5. apoptosis of NP
  6. calcification and extrusion of NP
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are the most common localizations for IVDH type I

A
  1. thoracolumbar
  2. T11-L2
  3. cervical spine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

IVDH type I clinical signs

A
  • hyperesthesia
  • ataxia
  • paraparesis
  • paraplegia

can be pain only if not progressed to affect limb function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

IVDH type I diagnosis

A
  1. surgery rads - narrowing of IVD space + disc mineralization
  2. MRI - definitive diagnosis; dark and narrow disc spaces w/ extrusion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

IVDH type I treatment

A

conservative: cage rest 4-6 weeks, pain management (no steroids)

surgical: hemilaminectomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

discospondylitis description

A

infection of the cartilaginous endplates in the intervertebral space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

discospondylitis signalment

A

breeds: large (esp. GSDs)
age: young to middle aged

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

discospondylitis clinical signs

A

usually acute but can be chronic if untreated

  • spinal pain (hyperesthesia)
  • fever + weight loss
  • +/- neuro signs

usually NO paresis/paralysis or deficits - typically pain only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

discospondylitis pathogenesis

A

genetic, trauma, migrating grass awns, dental disease, etc

bacterial: brucella canis, staph, strep, E. coli
fungal: aspergillus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

discospondylitis diagnostics

A
  1. radiographs - end plate destruction
  2. MRI/CT
  3. blood or urine culture
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

discospondylitis treatment

A

long term antibiotics (6-8 weeks)
activity restriction
pain management
recheck rads to monitor progression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

discospondylitis prognosis

A

good if no endocarditis

poor if fungal or brucella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

infectious meningomyelitis

A

infection of the spinal cord

agents: distemper, FIP, FeLV

hematogenous spread or virus entry into CNS

16
Q

non-infectious meningomyelitis

A

sterile inflammation of the spinal cord (MUO vs SRMA)

can be primary or secondary - unknown pathogenesis

17
Q

GME of the spinal cord

A

disseminated, immune mediated inflammation of the spinal cord

breeds: small
age: young to middle aged

multifocal intracranial or spinal signs

dx: MRI + CSF
tx: immunosuppressive corticosteroid dose

18
Q

SRMA (steroid responsive meningitis arteritis) of the spinal cord

A

mostly affects the cervical spine

breed: large
age: young (<2 years)

dx: MRI + CSF
tx: immunosuppressive corticosteroid dose