Spinal and Nerve Root Disease Flashcards
DDx of spinal cord lesions:
Intrinsic:
- Infection - 2
- Inflammation - 3
- Malignancy - 1
- Happens in the brain - 1
- Degenerative
- A type of deficiency
EBV, syphilis
Transverse myelitis, MS, NMO
Primary tumour
Spinal stroke
Spino-cerebellar ataxia
B12 deficiency
DDx of spinal cord lesions:
Extrinsic:
- Malignancy
- Blood
- Infection may cause what?
- Obvious cause from an accident for example?
Tumour (either local or mets)
Haematoma
Abscess
Trauma
Spine and nerve root anatomy:
Grey matter:
- What does it look like?
- What type of nuclei does the dorsal horn and ventral horn contain?
White matter:
- Where are ascending (sensory and afferent) tracts?
- Where are descending (motor and efferent) tracts?
Butterfly shape
D - sensory nuclei
V - motor nuclei
Dorsal and external lateral cord
Route of a spine nerve:
What information does the dorsal and ventral root carry?
The 2 roots form a single spinal nerve. then split into the anterior rami and the posterior rami. What do these 2 supply?
D - sensory
V - motor
Anterior - most of the body
Posterior - the back
Injury levels:
Why do you make sure you scan a big portion of the spine, especially for lower presentations?
The lesion itself is often higher than the sensory level and is truer the lower down the lesion is.
This is because the nerve roots move down alongside the spine before exiting the spinal cord.
Injury levels:
Around what level is the phrenic nerve injured and what will that lead to?
Above what level do the intercostal muscles become effected?
What is the sympathetic trunk?
What range of levels does it exit in?
What may injury to it cause?
C3-5
Impaired ventilation - diaphragm
T8
A paired bundle of nerve fibres that run from the base of the skull to the coccyx. The sympathetic trunk lies just lateral to the vertebral bodies for the entire length of the vertebral column.
T1-L2
Autonomic dysfunction, including neurogenic shock
Spinal cord compression:
Define?
Causes:
- Non-neoplastic - 4
- Neoplastic - list common origination of mets
Pressure on the spinal cord or the surrounding CSF or vascular system.
Trauma
Vertebral crush fracture due to osteoporosis
Slipped disc
Infection - discitis, epidural abscess, TB
Breasts Lung Prostate Myeloma Renal cell
Spinal cord compression:
S+S:
First symptom
What makes this worse? - 2
Second symptom - sensory loss:
- Sym/assym
- How many dermatomes are effected?
- Is it on the same sensory level as the lesion?
Third symptom - motor loss:
- Where?
- Reflexes?
- Tone?
- What about sphincters?
What patient should this be a red flag in?
Back pain + worse on lying/coughing
Symmetrical sensory loss
1-2 dermatomes below lesions - remember they move down before exiting
Legs weakness
Hyperreflexia
Hypertonia
Sphincter dysfunction (hesitancy, frequency, and later painless retention)
CANCER PATIENTS!! - They present with worsening back pain or impaired mobility/sensation
Spinal cord compression:
Management:
- Who needs to be contacted and for what?
- What drug is given?
- What scan is only useful in spinal trauma?
- What scan will be used if there has been a history of trauma?
Neurosurgery
Dexamethasone (loading dose then daily)
MRI whole spine
Spine X-ray
Spinal stenosis:
What is it?
What part of the spine does this usually happen in?
What else is involved apart from the spinal cord?
Spinal degeneration (spondylosis), particularly of the facet joints, resulting in narrowing of the spinal canal.
Lumbar region
The nerve roots themselves, therefore, CORD+ROOTS
Spinal stenosis:
What type of leg pain do you get?
What else happens to the legs?
Where does the pain radiate to?
What position makes the symptoms better or worse?
Neurogenic intermittent claudication - exertional leg pain with aching and heaviness
Weakness and numbness
Relieved by flexion - sitting or lying down, walking uphill
Worsened by extension - standing up, arching back q
Spinal stenosis:
Management:
Non-surgical:
- What can be worn to help?
- What can be given for pain and inflammation?
- What if the previous meds aren’t enough?
A brace - used to limit bending and twisting and assist in carrying some of the weight the discs normally withstand. Bracing for lumbar spinal stenosis aims to reduce pressure on and limit micro-motions in the lower spine, both of which can cause nerve root irritation and radicular pain.
NSAIDs
Epidural corticosteroids
Spinal stenosis:
Management:
Surgical:
- One option!
- Spinal surgery risk?
Decompression in those with debilitating symptoms
Nerve damage
Continued pain
Infection
CSF leak
Radiculopathy:
What is it?
Nerve ROOT compression
Disc degeneration and HERNIATION
Spondylosis (vertebral degeneration)
Trauma
Radiculopathy:
Sensory symptoms:
You get pain:
- How would patients describe the pain?
What other symptoms will they complain of?
Where would these symptoms be?
Sharp
Stabbing
Electrical
Hot
Numbness or paresthesia
Dermatomal distribution
Radiculopathy:
Motor symptoms - what will happen?
Are symptoms usually uni/bilateral?
What may happen if the cord is compressed at that level?
Weak in myotome
Unilateral
UMN signs below the lesion
Radiculopathy:
What symptoms do you have with cervical radiculopathy?
What does lumbar radiculopathy cause 90% of?
Neck and upper limb symptoms
Sciatica (L4-S3)
Radiculopathy - SCIATICA:
Where do you have pain? - 3 Where is the pain worst? Uni/bi? Where does the pain radiate to? What reproduces the pain that is done in the spinal examination? What 2 other symptoms do they have? Reflexes? How may muscle weakness present?
Buttock and leg pain > back pain
Unilateral
Foot and toes
Straight leg raise
Numbness and paraesthesia
Hyporeflexia
Muscle weakness = foot drop
Radiculopathy:
Management:
It is initially managed by mechanical back pain. What does this involve?
What is the next step if the pain is not improving?
Same as mechanical back pain - no need for imaging: > Continue ADLs > Patient education > Physiotherapy > Psychological support
Analgesia - paracetamol, NSAIDs, weak opioids or neuropathic (amitriptyline, gabapentin)
Radiculopathy:
Management:
Was is done for refractory sciatica that is severe, acute and persists >1-2 wks?
What will surgery improve?
What should be done for someone with refractory cervical radiculopathy (>6 wks) or with objective neurological signs?
Epidural steroids or local anaesthetic injections
Refer for MRI
Possible epidural injections
Surgery
CHECK RHEUMATOLOGY FOR MECHANICAL BACK PAIN
CHECK RHEUMATOLOGY FOR MECHANICAL BACK PAIN