Metabolic Bone Diseases - Paget's Disease Flashcards

1
Q

There is increased bone marrow turnover due to increased number of osteoclasts and blasts. What does this lead to?

A

Bone enlargement
Deformity
Weakness

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2
Q

It is asymptomatic in 70%.

What type of pain do they feel?

Where do they typically get deformity?

A

Deep boring pain

Pelvis
Lumbar spine 
Skull 
Femur 
Tibia
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3
Q

Complications:

Why do they get deafness and root compression?

A

Due to bone overgrowth causing nerve compression

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4
Q

What is the main Rx?

A

Alendronic acid

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