Metabolic Bone Diseases - Paget's Disease Flashcards
1
Q
There is increased bone marrow turnover due to increased number of osteoclasts and blasts. What does this lead to?
A
Bone enlargement
Deformity
Weakness
2
Q
It is asymptomatic in 70%.
What type of pain do they feel?
Where do they typically get deformity?
A
Deep boring pain
Pelvis Lumbar spine Skull Femur Tibia
3
Q
Complications:
Why do they get deafness and root compression?
A
Due to bone overgrowth causing nerve compression
4
Q
What is the main Rx?
A
Alendronic acid