Spectrum of commonly used agents Flashcards
What organisms does benzyl penicillin work against?
Gram positive organisms
Amoxicillin works against which organisms?
Gram negative organisms
Co-amoxiclav works against which organisms?
Beta-lactamase producing coliforms
Flucloxacillin works against which organisms?
Staphylococcal Beta-lactamase
What spectrum penicillin is piperacillin?
Broad spectrum
Piperacillin works against which organisms?
Gram negative organisms
Imipenem and meropenem are close relatives of what?
Penicillins
As generation number of cephalosporins increase, resistance to gram negative organisms does what?
Increases
As generation number of cephalosporins increase, resistance to gram positive organisms does what?
Decreases
Name an example of an aminoglycoside
Gentamicin
Aminoglycosides work against what?
Gram negative organisms
Glycopeptides work against what?
Gram positive organisms
Give two examples of glycopeptides
Vancomycin and teicoplanin
Macrolides work against what?
Gram positive organisms
Linezolid works against what?
MRSA
What can linezolid cause?
Bone marrow suppression
Tetracyclines are what type of spectrum?
Broad spectrum agents
Tetracyclines inhibit what?
Bacterial protein synthesis
What do polyenes bind to?
Ergosterol
Nystatin can only be administered in what way?
Topically
Name the 2 groups of ant-fungal drugs that suppress ergosterol synthesis
Azoles
Allylamines
What is used to treat aspergillosis?
Voriconazole
Itraconazole
What is terbinafine used for?
To fight fungal infection of the skin and nails
New generations of quinolones are effective against what?
Gram negative organisms
What are the 2 main mechanisms in resistance to B-lactams?
B-lactamase production
Alteration of PBP target site
Name 2 urinary tract agents
Nalidixic acid
Nitrofurantoin
Immediate hypersensitivity is mediated by what antibody?
IgE
Thrush occurs when what yeast is overgrown?
Candida Albicans
