Spectrum of commonly used agents

Question 1

What organisms does benzyl penicillin work against?

Answer 1

Gram positive organisms

Question 2

Amoxicillin works against which organisms?

Answer 2

Gram negative organisms

Question 3

Co-amoxiclav works against which organisms?

Answer 3

Beta-lactamase producing coliforms

Question 4

Flucloxacillin works against which organisms?

Answer 4

Staphylococcal Beta-lactamase

Question 5

What spectrum penicillin is piperacillin?

Answer 5

Broad spectrum

Question 6

Piperacillin works against which organisms?

Answer 6

Gram negative organisms

Question 7

Imipenem and meropenem are close relatives of what?

Answer 7

Penicillins

Question 8

As generation number of cephalosporins increase, resistance to gram negative organisms does what?

Answer 8

Increases

Question 9

As generation number of cephalosporins increase, resistance to gram positive organisms does what?

Answer 9

Decreases

Question 10

Name an example of an aminoglycoside

Answer 10

Gentamicin

Question 11

Aminoglycosides work against what?

Answer 11

Gram negative organisms

Question 12

Glycopeptides work against what?

Answer 12

Gram positive organisms

Question 13

Give two examples of glycopeptides

Answer 13

Vancomycin and teicoplanin

Question 14

Macrolides work against what?

Answer 14

Gram positive organisms

Question 15

Linezolid works against what?

Answer 15

MRSA

Question 16

What can linezolid cause?

Answer 16

Bone marrow suppression

Question 17

Tetracyclines are what type of spectrum?

Answer 17

Broad spectrum agents

Question 18

Tetracyclines inhibit what?

Answer 18

Bacterial protein synthesis

Question 19

What do polyenes bind to?

Answer 19

Ergosterol

Question 20

Nystatin can only be administered in what way?

Answer 20

Topically

Question 21

Name the 2 groups of ant-fungal drugs that suppress ergosterol synthesis

Answer 21

Azoles

Allylamines

Question 22

What is used to treat aspergillosis?

Answer 22

Voriconazole

Itraconazole

Question 23

What is terbinafine used for?

Answer 23

To fight fungal infection of the skin and nails

Question 24

New generations of quinolones are effective against what?

Answer 24

Gram negative organisms

Question 25

What are the 2 main mechanisms in resistance to B-lactams?

Answer 25

B-lactamase production

Alteration of PBP target site

Question 26

Name 2 urinary tract agents

Answer 26

Nalidixic acid

Nitrofurantoin

Question 27

Immediate hypersensitivity is mediated by what antibody?

Answer 27

IgE

Question 28

Thrush occurs when what yeast is overgrown?

Answer 28

Candida Albicans