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Pharmacology > specific toxicity treatments > Flashcards

specific toxicity treatments Flashcards

1
Q

acetaminophen toxicity - treatment

A

N-acetylcysteine (replenish glutathione)

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2
Q

AChE inhibitors, organophosphates toxicity - treatment

A

Atropine>pralidoxime

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3
Q

Antimuscarinic, anticholinergic agonists toxicity - treatment

A
  1. Physostygmine

2. control hyperthermia

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4
Q

Amphetamines toxicity - treatment

A

NH4CL (acidify urine)

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5
Q

Arsenic toxicity - treatment

A

dimercaprol, succimer

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6
Q

Benzodiazepines toxicity - treatment

A

Flumazenil

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7
Q

β-blockers toxicity - treatment

A

saline, atropine, glucagon

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8
Q

Carbon monoxide toxicity - treatment

A

100% 02, hyperbaric oxygen

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9
Q

Copper toxicity - treatment

A

penicillamine, trentine

oral zinc

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10
Q

Cyanide toxicity - treatment

A

Nitrate + thiosulfate, hydroxocobalamin

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11
Q

Digitalis (digoxin) toxicity - treatment

A

Anti-dig Fad fragments

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12
Q

Gold toxicity - treatment

A

penicillamine, diercaprol (BAL), succimer

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13
Q

heparin toxicity - treatment

A

protamine sulfate

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14
Q

flumazenil is the antidote for

A

benzodiazepines

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15
Q

iron toxicity - treatment

A

deferoxamine, derasirox, deferiprone, repeated phlebotomy

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16
Q

lead toxicity - treatment

A

EDTA, dimercaprol, succimer, penicillamine

17
Q

Mercury toxicity - treatment

A

dimercaprol, succimer

18
Q

Methemoglobin toxicity - treatment

A

Methylene blue, vitamin C

19
Q

Opioids toxicity - treatment

A

naloxone

20
Q

Salicylates toxicity - treatment

A

NaHCO3 (alkalinize urine), dyalisis

21
Q

TCAs toxicity - treatment

A

NaHCO3

22
Q

Warfarin toxicity - treatment

A 
vitamin K (delayed effect)
fresh frozen plasma (immediate)
23
Q

Bivalirudin toxicity - treatment

A

not specific –> can attempt to use activated prothrombin complex concentrates (PCC) and/or fibrinolytics (eg. traxenamic acid)

24
Q

Methanol, ethynele glycol (antifreeze) toxicity - treatment

A

fomepizole>ethanol, dialysis

25
Q

arsenic, copper, gold, iron, lead, mercury toxicity - treatment

A

arsenic –> dimercaprol, succimer
copper –> penicillamine, trentine, oral zinc
lead –> EDTA, dimercaprol, succimer, penicillamine
gold –> penicillamine, diercaprol (BAL), succimer
mercury –> dimercaprol, succimer
iron –> deferoxamine, derasirox, deferiprone, repeated phlebotomy

Pharmacology (9 decks)

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