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-Electrodiagnostics > Specific Polyneuropathies > Flashcards

Specific Polyneuropathies Flashcards

1
Q

2 mixed axonal and demyelinating neuropathies

A

Diabetes and uremia

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2
Q

Nerve biopsy finding of leprosy

A

Foamy histiocyte invasion

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3
Q

3 different uniform demyelinating mixed sensorimotor neuropathies

A

HMSN I, III, IV

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4
Q

Which axonal sensorimotor neuropathy causes uveitis

A

Sarcoidosis

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5
Q

What kind of neuropathy is multifocal motor neuropathy

A

Demyelinating motor neuropathy

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6
Q

What distinguishes HMSN II from the other ones?

A

Less foot intrinsic involvement.

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7
Q

3 segmental demyelinating motor and sensory neuropathies

A

AIDP (GBS), CIDP, leprosy (Hansen’s disease)

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8
Q

What would CSF analysis show for HMSN I, III, IV?

A

Increased protein

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9
Q

Is weakness in CIDP more proximal or distal

A

Proximal

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10
Q

Which axonal sensorimotor neuropathy has foot or wrist drop

A

EtOH

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11
Q

Which toxin causes blue lines in gums

A

Lead

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12
Q

What would nerve biopsy show for HMSN I, III, IV

A

Onion bulb formation

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13
Q

Which axonal sensory neuropathy results in nephrotoxicity

A

Cis-platinum toxicity

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14
Q

3 axonal sensorimotor neuropathies

A

EtOH, amyloidosis, sarcoidosis

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15
Q

Which toxin causes lower limb weakness

A

Vincristine

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16
Q

3 main toxins that lead to neuropathy

A

Lead, vincristine, dapsone

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17
Q

4 axonal sensory neuropathies

A

Cis-platinum toxicity, friedreich’s ataxia, sjogren’s, Vit b6 toxicity

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18
Q

Most common CN affected in AIDP

A

CN 7

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19
Q

Which axonal sensory neuropathy results in WC use by 16 yo

A

Friedreich’s ataxia

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20
Q

Nerve biopsy of axonal sensory neuropathies

A

Abnormally large axons

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21
Q

Which HMSN has retinitis pigmentosa

A

HMSN IV

22
Q

Which axonal sensorimotor neuropathy has birefringence with congo red staining

A

Amyloidosis

23
Q

HMSN I, III, IV are also known as

A 
I = Charcot Marie Tooth
III = Dejerine Sottas
IV = Refsum's Disease
24
Q

UA findings seen in porphyria

A

Deep red

25
Q

Which axonal sensory neuropathy has pes cavus deformity

A

Friedreich’s ataxia

26
Q

Amyloidosis neuropathy results from amyloid deposits in the …

A

DRG

27
Q

3 Axonal motor > sensory neuropathies

A
  1. Porphyria
  2. Toxins
  3. HMSN II
28
Q

First electrodiagnostic sign of CIDP

A

Abnormal F-wave

29
Q

Which toxin causes progressive onset upper limb weakness

A

Lead

30
Q

Which axonal sensory neuropathy is associated with RA

A

Sjogren’s

31
Q

Most common cause of peripheral neuropathy worldwide

A

Leprosy

32
Q

Which axonal sensorimotor neuropathy causes bilateral hilar adenopathy

A

Sarcoidosis

33
Q

Which HMSN has floppy baby

A

HMSN III

34
Q

Which toxin causes ascending foot and hand neuropathy

A

Dapsone

35
Q

Which toxin causes blindness and epilepsy

A

Lead

36
Q

Which of HMSN has distal motor more than sensory of the LE > UE in stocking glove pattern

A

HMSN I

37
Q

Etiology of porphyria

A

Defect in heme synthesis

38
Q

Which toxin causes basophilic stippling in RBCs

A

Lead

39
Q

Which HMSN has bilateral foot drop

A

HMSN I

40
Q

EDx finding indicative of multifocal motor neuropathy

A

Multifocal motor conduction block

41
Q

Which toxin causes wrist drop

A

Lead

42
Q

Which of HMSN is autosomal dominant vs recessive

A

I, II = dominant

III, IV = recessive

43
Q

Which of HMSN I, III, IV has later onset?

A

HMSN IV - 3rd decade. The other 2 are within 1st 2 years

44
Q

What distinguishes demyelinating AIDP from axonal AIDP?

A

Axonal is areflexic

45
Q

Which toxin causes methemoglobinemia

A

Dapsone

46
Q

Which axonal sensorimotor neuropathy results in purpura

A

Amyloidosis

47
Q

Most common type of HIV related neuropathy

A

Distal symmetric polyneuropathy

48
Q

Csf findings of AIDP and CIDP

A

Increased protein

49
Q

What treatment do you use for CIDP that you do not use for AIDP

A

steroids

50
Q

Which axonal sensory neuropathy has lhermitte’s sign

A

B6 toxicity

51
Q

Treatment of AIDP

A

Plasmapharesis, IVIG

-Electrodiagnostics (20 decks)

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