Myopathies overview Flashcards

1
Q

5 dystrophic myopathies

A
  1. Duchenne
  2. Becker
  3. Fascioscapulohumeral
  4. Limb-girdle
  5. Myotonic
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2
Q

In normal muscle, where is dystrophin found?

A

Sarcolemma

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3
Q

What is function of dystrophin in normal muscle

A

Provides mechanical support for muscle membrane cytoskeleton

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4
Q

Painless delayed relaxation of skeletal muscles following voluntary contraction

A

Myotonia

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5
Q

What exacerbates myotonia

A

Cold

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6
Q

What relieves myotonia

A

Exercise, dilantin, procainamide and CCBs

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7
Q

Fixed deformity of the extremities a due to intrauterine hypomobility

A

Arthrogryposis

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8
Q

Hallmark sign of myopathy is…

A

Inability to generate forceful contraction

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9
Q

SNAP finding of myopathy

A

Normal

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10
Q

CMAP finding of myopathy

A

Decreased amplitude, normal latencies and CV

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11
Q

EMG finding of short duration, small amplitude MUAP is due to

A

Loss of muscle fibers

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12
Q

Emg finding of long duration, large amplitude MUAP is due to…

A

Collateral sprouting

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