Myopathies overview Flashcards
5 dystrophic myopathies
- Duchenne
- Becker
- Fascioscapulohumeral
- Limb-girdle
- Myotonic
In normal muscle, where is dystrophin found?
Sarcolemma
What is function of dystrophin in normal muscle
Provides mechanical support for muscle membrane cytoskeleton
Painless delayed relaxation of skeletal muscles following voluntary contraction
Myotonia
What exacerbates myotonia
Cold
What relieves myotonia
Exercise, dilantin, procainamide and CCBs
Fixed deformity of the extremities a due to intrauterine hypomobility
Arthrogryposis
Hallmark sign of myopathy is…
Inability to generate forceful contraction
SNAP finding of myopathy
Normal
CMAP finding of myopathy
Decreased amplitude, normal latencies and CV
EMG finding of short duration, small amplitude MUAP is due to
Loss of muscle fibers
Emg finding of long duration, large amplitude MUAP is due to…
Collateral sprouting