Specific or Acquired Immunity Flashcards
Specific or acquired immunity involves the production of what?
Antibodies against specific foreign antigens by lymphocytes
Antigens (antibody generating substances) are usually what?
Large complex molecules
Smaller molecules that stimulate antibody production are called what?
Haptens
Haptens only stimulate antibody production if it is attached to what?
A protein for initial presentation to immune system
Specific immune responses rely on what?
Lymphocytes
Specific immunity may be mediated by what?
Humoral (antibody) responses
Cell-mediated (no antibodies) responses
Some tissue will tolerate antigens without eliciting what?
Inflammatory Response
The tissure that tolerate antigens with eliciting inflammatory responses are what
Immunologically privileged
- brain
- eye
- testis
- fetus
Products of immune cells include what?
Tumor necrosis factor
Immunoglobulins
Cytokines
Transforming growth factor
Cytokines include what?
Lymphokines
Interferons
Interlukins 1-18
Cytokines are produced by what?
Inflammatory cells in general
Lymphokines are produced from what?
Lymphocytes
Antibody mediated immunity depends on what?
B Lymphocytes
T Lymphocytes
B lymphocytes are involved in what?
Generation of humoral immunity
B lymphocytes mature where?
Bone Marrow
B Lymphocytes are also known as what?
Plasma Cells
B lymphocytes make antibodies in the form of what?
Immunoglobulins
T lymphocytes include how many of circulating lymphocytes?
95%
T lymphocytes mature where?
Thymus
T lymphocytes are involved in what?
Cell-mediated immunity
T lymphocytes are produced through the production of what
Activated T lymphocytes