Nonspecific or Innate Immunity

Question 1

Non specific or Innate immunity depends on physical barriers such as?

Answer 1

Mechanical- skin, GI, respiratory, GU epithelium

Chemical- acid pH in stomach and vagina

Question 2

There are also vascular and phagocytic responses which are a result of what?

Answer 2

Injured or infected cells

Question 3

What system is involved as it is designed to defend against infection by promoting phagocytosis and killing cells directly?

Answer 3

Complement System

Question 4

Non specific or innate contain certain bacteria that carry surface molecules which activate what?

Answer 4

Complement system of plasma proteins

Question 5

Complement activation produce a series of what activities?

Answer 5

Opsonization
Inflammation
Lysis
Chemotaxis
Agglutination
Neutralization

Question 6

Opsonization makes target cells what?

Answer 6

More susceptible to phagocytosis

Question 7

What binds to the surface of bacteria?

Answer 7

Opsonins which are complement fragments

Question 8

Phagocytic cells with receptors for complement fragments become attached to what?

Answer 8

Opsonized bacteria

Question 9

When phagocytic cells become attached to opsonized bacteria it increases the binding of what?

Answer 9

Bacteria for phagocytosis (C3b)

Question 10

Inflammation is due to activation of what?

Answer 10

Mast cells in anaphylaxis (C3a, C4a and C5a)

Question 11

Chemotaxis does what?

Answer 11

Attracts specific WBCs to area of damage

Question 12

Agglutination does what?

Answer 12

Changes surface of invading bacteria making them sticky

Question 13

Neutralization of toxic sites is found where?

Answer 13

Surface of antigen