Humoral Immunity Flashcards
Antibodies belong to a class of proteins called what?
Immunoglobulins (Ig) in shape of Y
The Fc (tail of Y) region determine what?
Type of immunoglobulin
- IgG
- IgA
- IgM
- IgD
- IgE
IgG is the most abundant in circulation and promotes what?
Phagocytosis and Cell Lysis
IgG also confers what?
Passive Immunity
IgA is present where?
Saliva
Tears
Breast Milk
IgA is most what?
Most abundantly produced in general
IgM is secreted early on and promotes what?
Agglutination
Phagocytosis
Cell Lysis
IgD are found where?
Surface of antibody on B lymphocytes
What is the role of IgD?
Role is unclear
IgE is important where?
Parasitic infections
Allergic Responses
The Fab (arms of Y) is responsible for what?
Antigen binding specificity
Antibodies bind to antigens thus promoting what?
Their own destruction
Antibodies that bind to antigens promote their own destruction directly by what?
Precipitating soluble antigens
Lysis of membranes
Agglutination (clumping together)
Neutralization of toxins or inactivation of some viruses
