Specific diseases and their skin manifestations

Question 1

Crohn’s Disease:

What lesions on the shin can occur?

What necrotic ulcer can occur?

Answer 1

Erythema nodosum

Pyoderma gangrenosum

Question 2

Coeliac Disease:

Dermatitis herpetiformis:

• Is it itchy?
• Where does it occur?

Answer 2

Yes, very itchy

Elbows
Knees
Scalp

Question 3

Hypothyroidism - what happens around the shin area?

Answer 3

Pretibial myxoedema

Question 4

Malabsorption:

What may be seen on the nails?

Answer 4

Leuconychia - white lines on nails

Question 5

Acanthosis nigricans:

What is it?

What endocrine disease is it seen in?

What cancer is it associated with?

Answer 5

Brown-to-black, poorly defined, velvety hyperpigmentation of the skin. It is usually found in body folds, such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas.

DM

Gastric cancer

Question 6

What cancer is dry scaly skin associated with?

Answer 6

Lymphoma

Question 7

Trousseau syndrome is an acquired blood clotting disorder that results in migratory thrombophlebitis (inflammation of a vein due to a blood clot).

What cancer is it linked to?

Answer 7

Pancreatic cancer