Medium Vasculitis

Question 1

Polyarteritis Nodosa (PAN):

What does the necrotising vasculitis lead to?

S+S:

• Systemic symptoms
• What is seen on the skin?
• There is a range of presentations of vasculitis. Look at vasculitis deck on it’s own!

Answer 1

Aneurysms, bleeds and thrombosis

Fatigue 
Fever 
Weight loss 
Headache 
Myalgia 

Purpura

Question 2

Polyarteritis Nodosa (PAN):

How is it treated?

Answer 2

Steroids + methotrexate

Question 3

Kawasaki Disease:

When age is it most common?

S+S:

• What systemic sign do they have?
• What becomes inflamed near the eye?
• Rash - type, where does it start and progress to?
• How is the tongue described?

Kawasaki’s Disease

Management:
Acute
Long term - why?

Answer 3

Age 2

Fever

Dry bilateral conjunctivitis

A non-vesicular, desquamating rash which starts at
extremities (inc palms and soles)

Aspirin and IVIG

Risk of Reyes with aspirin use in children. Aspirin not used.

Lifelong aspirin as 25% develop coronary artery aneurysms and are at risk of early MI