Specific Antidotes Flashcards by Patricia Pastrana

Q

Cholinesterase inhibitors, organophosphates

A

Atropine followed by Pralidoxime

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Q

Amphetamines

A

NH4Cl (to acidify urine)

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Q

Antimuscarinic, anticholinergic agents

A

Physostigmine salicylate, Control hyperthermia

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Q

Benzodiazepines

A

Flumazenil

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Q

Beta-blockers

A

Glucagon

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Q

Carbon monoxide

A

100% Oxygen, hyperbaric Oxygen

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Q

Copper, Arsenic, Gold

A

Penicillamine

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Q

Cyanide

A

Nitrite + thiosulfate, Hydroxycobalamin

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Q

Digitalis

A

Anti-dig Fab fragments

Stop digitalis, Correct K levels, Give Mg

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Q

Heparin

A

Protamine sulfate

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Q

Iron

A

Deferoxamine, Deferasirox

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Q

Lead

A

EDTA, dimercaprol, succimer, Penicillamine

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Q

Mercury, arsenic, gold

A

Dimercaprol, succimer

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Q

Methanol, ethylene glycol (antifreeze)

A

Fomepizole > Ethanol, dialysis

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Q

Methemoglobin

A

Methylene blue, vitamin C

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Q

Opioids

A

Naloxone

Q

Salicylates

A

NaHCO3 (alkalinize urine), dialysis

Q

TCAs

A

NaHCO3 (alkalinize urine)

Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

Q

Warfarin

A

Vitamin K, plasma (FFP if active bleeding)

Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

Q

Methotrexate (myelosuppression)

A

Leucovorin

Q

5-fluouracil (myelosuppression)

A

Uridine

Q

Malignant hyperthermia (caused by inhaled anesthetics)

A

Dantrolene

Q

SSRI (Serotonin syndrome)

A

Cyproheptadine (5-HT2 receptor antagonist)