Special Topics Flashcards

1
Q

Puberty

A

Reproductive maturation guided by a sequence of timed neuroendocrine events

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2
Q

Adolescence

A

Transitional period between childhood and adulthood. Psychological, cognitive, social and cultural aspects

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3
Q

What is critical in puberty?

A

Timing

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4
Q

What are the integration cues of puberty?

A

Metabolic
Social
Environmental

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5
Q

What makes the consequences of puberty energetically expensive?

A

Defense of territory or partner

Pregnancy or caregiving

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6
Q

Adrenarche

A

Adrenal androgen secretion (DHEAS)

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7
Q

Gonadarche

A

Gonadal production of steroid hormones

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8
Q

Thelarche

A

Breast development in girls

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9
Q

Pubarche

A

Auxiliary and pubic hair growth

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10
Q

Menarche

A

Onset of menstruation

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11
Q

What is the first overt sign of puberty?

A

Thelarche in girls and testicular enlargement in boys

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12
Q

What is the age of onset of puberty in girls?

A

8-12

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13
Q

What is the age of onset of puberty in boys?

A

9-14

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14
Q

How long does the puberty transition last?

A

3-4 years

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15
Q

What are the physical changes that males experience after/during puberty?

A
Growth spurt
Increase in lean muscle mass
Changes in body composition 
Increase in penile length and first ejaculation 
Pubic hair 
Testicular enlargement
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16
Q

What are the physical changes experienced by girls during/after puberty?

A
Growth spurt
Breast development 
Changes in body composition 
Pubic hair
Menarche 
Increase in fat mass
17
Q

What does early menarche risk?

A

Risk factor for breast cancer, CVD, depression, diabetes and all cause mortality

18
Q

What does early puberty in boys risk?

A

Testicular cancer/psychosocial distress

19
Q

Central precocious puberty

A

Early maturation of HPG axis
GnRH dependent
Tumors, chronic sex steroid exposure
60% idiopathic

20
Q

Peripheral precocious puberty

A

Early hormone production from peripheral glands

21
Q

What does puberty onset require?

A

Finely tuned temporal control of GnRH release from neurons in the hypothalamus
Strong genetic component to the timing of puberty

22
Q

What is central to gonadal maturation?

A

GnRH neurons