Special Reading: Peptidoglycan Biosynthesis

Question 1

Preexisting peptidoglycan has to be temporarily ______ which allows newly synthesized peptidoglycan

Answer 1

severed

Question 2

In cocci, new cell wall material grows out opposite direction from ____ ____

Answer 2

Ftsz ring

Question 3

hydrophobic C55 alcohol bonded to NAG/NAM/Pentapeptide Precursor

Answer 3

Bactoprenol

Question 4

transports pentapeptide precursor across cytoplasmic/inner membrane by disguising them as hydrophobic

Answer 4

Bactoprenol

Question 5

enzymes bactoprenol interact with outside of the cell

Answer 5

Transglycosylases

Question 6

Insert peptidoglycan precursors into the growing part of the cell wall and catalyze the glycosidic bond formation

Answer 6

Transglycosylases

Question 7

small gaps in existing peptidoglycan are made by these enzymes

Answer 7

autolysins

Question 8

function to hydrolyze bonds that connect NAG and NAM in the peptidoglycan backbone

Answer 8

autolysins

Question 9

the junction between new and old peptidoglycan forms a ridge on the cell wall of gram + bacteria

Answer 9

wall band

Question 10

Final step in peptidoglycan synthesis

Answer 10

transpeptidation

Question 11

transpeptidation reaction is inhibited by __________

Answer 11

penicillin

Question 12

transpeptidation forms _____ ________ bonds

Answer 12

cross-linking bonds

Question 13

What are two examples of bacteria of where cross-linking peptide bonds are form?

Answer 13

Escherichia coli and Vibrio cholerae

Question 14

What are the amino acids of the cross-linking peptide bond formed between?

Answer 14

Diaminopimelic acid and alanine