Sources of drugs and drug nomenclature Flashcards
Drugs may be ……… , ………. and ……….
- solid (eg, aspirin),
- liquid (eg, ethanol),
- gaseous (eg, nitrous oxide).
what are the factors that often determine the best route of administration ?
- solid (eg, aspirin),
- liquid (eg, ethanol),
- gaseous (eg, nitrous oxide).
مني متاكدة من كتابت المهم شوفي
المرجع slide1
Chemical name, Generic name ,Trade name
are
Types of drug names
chemicalmake-upofcompound
• usually too complex for people to remember
Chemical name:
simpler than the chemical name - derived from the chemical name itself - easier to remember
Generic name:
• Name by which drug is marketed
Trade name:
A single drug can have multiple ………..
Trade name
………… must be approved by FDA
Trade names
• Generic name for a drug is longer and more complex than the ……….
trade name
Drugs that can be purchased without prescription ( e.g. Acetaminophen, Ibuprofen,Aspirin..)
Over-The-Counter Drugs (OTC)
Drugs must be prescribed by a physician
Prescription drugs
Drugs could be classified according to
- Indications
Anti-diabetics
Antibiotics
2-. Mechanism of action Diuretics
Beta-blockers Vaso-dilators
Insulin secretors / Insulin secretagogues Bacterial cell wall synthesis inhbitors - Chemical Structure
Penicillin Sulfonylurea
A ……… is administered at a location distant from its intended site of action, eg, a pill given orally to relieve a TOOTHACHE.
Drug
A …………… must be transported from its site of administration to its site of action
useful drug
ماعرفت كيف اكتب السوال
A drug should be ………… or………… from the body at a reasonable rate so that its actions will be of appropriate duration.
inactivated or excreted
• The molecular size of drugs varies from
Drug Size
اتوقع كذا السوال والله مدري
المرجع
slide 8
very small (lithium ion, MW 7)
Drug Size
المرجع slide 8
to very large (eg, alteplase [t-PA], a protein of MW 59,050).
Drug Size
المرجع slide 8
Drugs interact with receptors by means of ……………. .. …………
chemical forces or bonds.
covalent, electrostatic, hydrophobic are
These are of three major types
slide 9 المرجع
very strong
not reversible
Covalent bonds
disappear from the blood after 15 minutes
• inhibit platelet aggregation–several days.
Covalent bonds
more common
weaker than covalent bonds.
variable from strong ionic bonds to weaker hydrogen bonds
Electrostatic bonding
quite weak
important in the interactions of highly lipid-soluble drugs with the lipids of cell membranes
Hydrophobic bonds
