Sos: Stomach Flashcards
bezoar
hair ball
4 regions of stomach
cardia
fundus
body (corpus)
Antrum (pyloric)
longitudinal folds within stomach mucosa that disappear when full
rugae
stomach pacemaker
ICC
initiates peristaltic movement of chyme
ICC
this stomach layer shortens the stomach
longitudinal layer
this stomach layer allows chyme to travel to pyloric sphincter
circular layer
this stomach layer allows for churning of chyme aiding in digestion
oblique layer
purpose of this in stomach is to reduce friction; thin connective tissue covered w/ serous epithelium
serosa
L: liver
middle: stomach
R: spleen
body of pancreas meets where
near stomach and duodenum
tail of pancreas always meets where
at root of spleen
explain Nutcracker syndrome
pt has enlarged testicle due to L renal vein being squeezed b/t aorta and superior mesenteric a. (pt. lost a lot of weight quickly and lost mesenteric fat)
2 retroperitoneal organs
pancreas and duodenum
lesser omentum 2 ligaments attach where
liver to stomach and liver to duodenum
nerve supply to stomach
vagus n. and celiac trunk
main arteries to stomach (name 5)
celiac a.
gastric a.
splenic a.
common and proper hepatic a.
gastroepiploic a.
lymphatic drainage of stomach goes where
Cisterna chyli to thoracic duct
what sympathetics supply the stomach
greater splanchnic nerves (T5-9)
how do you know you are in body of stomach when looking at histologic slide
see gastric pits and glands
4 main layers of stomach from inside to outside
mucosa
submucosa
muscularis propria/externa
serosa
body or antrum of stomach
antrum (not as dense)
3 layers of stomach mucosa
epithelium
lamina propria
muscularis mucosae
body (corpus) of stomach contains what 4 cells
parietal
chief
endocrine (D and G cells)
mucous
main cell in intestine
goblet cell
these cells make HCl and intrinsic factor
parietal cells
what is needed for resorption of vitamin B12
intrinsic factor
these cells make pepsinogen to pepsin
chief cells
D cells make what
somatostatin
G cells make what
gastrin
inhibits acid secretion
somatostatin
stimulates acid secretion
gastrin
what substance is secreted when we are hungry and increases appetite
Ghrelin
product used for protein digestion
pepsin
product used for carbohydrate digestion
amylase
product used for fat digestion
lipase
used to neutralize stomach acid before entering duodenum
HCO3 (bicarbonate)
part of stomach
L: body (corpus)
R: antrum
parietal cells found where
body (corpus of stomach)
gastrin found in what part of stomach
antrum
L arrow
R arrow
L: parietal cell (pink cytoplasm)
R: chief cell (blue cytoplasm)
what activates gastric activity in stomach
swallowed food
3 things that stimulate gastric secretion
Ach
histamine
gastrin
what shuts down HCl producing system of parietal cell
somatostatin and PGE2
intestinal phase of digestion happens when
when chyme enters
CCK increases or suppresses appetite
suppresses
insulin increases or suppresses appetite
suppresses
leptin stimulates or inhibits hunger
inhibits
CCK produced by
I cells in duodenum
stimulates gallbladder to contract and release bile and stimulates secretion of pancreatic juice
CCK
secretin’s action on the pancreas
secrete pancreatic enzymes
both secretin and CCK inhibit what
gastric secretion when contents are ready to enter duodenum
_____foods slow down stomach movement and digestion
fatty
2 places alcohol(ethanol) is absorbed
oral cavity and stomach
narrowing of pyloric sphincter
pyloric stenosis
baby projectile vomits after feeding
pyloric stenosis
mushroom sign
pyloric stenosis
B12 not able to be bound to intrinsic factor and absorbed and therefore vitamin B12 deficiency
Pernicious Anemia
swollen tongue, pallor, fatigue
anemia
____ deficiency can lead to pernicious anemia and megablastic anemia
vitamin B12
> 4 lobes in neutrophil
megaloblastic anemia
pernicious anemia is a type of _____anemia
megaloblastic
H. pylori
inflammation of stomach mucosa seen w/ sx’s of indigestion, N/V
acute gastritis
main cause of acute gastritis
H. pylori
hemorrhagic acute gastritis
hemorrhage acute gastritis
acute gastritis
normal stomach mucosa
N/V, indigestion + WEIGHT LOSS
chronic gastritis
histologic finding of chronic gastritis
metaplastic or dysplastic epithelium
intestinal metaplasia seen in chronic gastritis
Right?
chronic gastritis
chronic gastritis
painful ulcers of stomach +/or duodenum
peptic ulcer disease
H. pylori infections in _______ have greatest risk for _____
duodenum
peptic ulcer disease
______ increase the pain of an ulcer but do not cause an ulcer
spicy food
ulcer caused by increased intracranial pressure
Cushing ulcer
ulcer caused by severe burns
Curling ulcer
ulcer
what ulcer is life threatening
bleeding posterior wall gastric ulcer
posterior wall gastric ulcer risk bursting what artery
gastroduodenal a.
common cause of melena (black tarry stools due to blood)
bleeding ulcer
stomach bulges into chest; Z line elevates
sliding hiatal hernia
sliding hiatal hernia
untreated H.pylori infection; alcohol and smoking and blood type A can cause this
intestinal type adenocarcinoma (gastric carcinoma)
this type of gastric cancer is seen in older adults
intestinal type
hereditary associated w/ CDH1 gene mutation
diffuse type adenocarcinoma (gastric cancer)
this type of gastric cancer deals with younger adults
diffuse type
3 places to check before you know you have stomach cancer
supraclavicular node
periumbilical node
ovaries
another name for supraclavicular node
Virchow node
another name for periumbilical node
Sister Mary Joseph nodule
another name for mass around ovaries to identify gastric carcinoma
Krukenberg node
TNM staging for gastric cancers
tumor size
nodes
metastasis
intestinal type gastric carcinoma
metaplasia into dysplasia
intestinal type gastric carcinoma
metaplasia into dysplasia
intestinal type gastric carcinoma
thick walled stomach
diffuse type gastric carcinoma
spread of signet ring cells
diffuse type gastric carcinoma
diffuse type gastric carcinoma
diffuse type gastric carcinoma
signet ring cells