Somesthesis Flashcards
Light touch
Detected by cutaneous extero-receptors that are rapidly adapting (detect transient events)
Transmitted by A-beta fibers
Proprioception
Perception of body projections and movement (including info from muscles, joint capsules, ligaments, tendons, and vestibular system)
More deeply situated by groups I-a, I-b, and II afferents
Nervous system must compare output to muscle with input from muscle and tendons
Gross touch
Detected by cutaneous extra-receptors that are rapidly adapting (detect transient events)
Transmitted by A-beta and A-delta fibers
Temperature
Separate sets of fibers and thermoreceptors that respond to increases and decreases in skin temperature
Slowly adapting neurons
Cold receptors: A-delta and C fibers
Warmth receptors: unmyelinated afferents
Fast pain
Pain from cutaneous tissues comes from A-delta fibers
Muscle afferents
info about contractile status
Deep receptors
Joints and proprioception
Cutaneous receptors
Subserve tactile sensation
SI (primary somatosensory cortex)
Complete map of body represented in postcruciate gyrus, projects to primary motor cortex (MI)
Oral and facial projections (from VCM)
terminate more laterally
Trunk and limb projections (from VCL)
terminate medially
Slow pain
Pain from cutaneous tissues comes from C fibers
Dentin
Radially oriented tubules with odontoblasts protruding in at dento-pulpal interface
Changes in hydrodynamic pressure in tubules cause odontoblast to move -> afferents -> pain
A-delta = sharp localized pain
C = diffuse, poorly localized aching
Trigeminal ganglion
cell bodies of receptors which innervate facial skin and oral cavity, analogous to dorsal root ganglia; reflects 3 incoming branches (V1, 2, 3)
Subnucleus oralis
Division of V spinal nucleus
Represents oral cavity (tooth pulp, gingival, palate, buccal mucosa)
Mediates oral cavity reflexes (chewing and defensive)
Subnucleus interpolaris
Division of V spinal nucleus
Represents head and oral cavity
Mediates tactile facial reflexes
Subnucleus caudalis
Division of V spinal nucleus
Complete representation of face and oral cavity
Relay of pain and thermal sensation
C fibers
Lightly myelinated or unmyelinated
Smaller diameter axons, slower conducting
Pain and temperature
Spinothalamic tract
formed by axons that cross the spinal cord at levels in which their cell bodies are located
Interruption reduces pain and temp sensations contra laterally, targets ventrocaudal thalamus
Spinoreticular tract
many fibers terminate in medullary reticular formation, some relay in midbrain reticular formation, involved in arousal and motivational-affective reactions to nociceptive stimulation
Reticular
most primitive motor system
Tooth pulp
Contains endings of A-delta and C afferents -> pain
A-beta afferents -> non-painful sensations
Directly sensitive to mechanical disturbances
Nociceptors
pain receptors
Gracile fasiculus
Receives input from sacral, lumbar, and lower thoracic roots, representing lower trunk and legs
Pacinian corpuscle
Fast adapting A-beta touch fibers
Laminated with central neurotic, sensitive to minimal skin distortion (gingival)
More sensitive
Meissner’s corpuscle
Specialized fast adapting receptors
Located within dermal papillae of glabrous skin and supplied by A-beta class fibers
Less sensitive
Hair cells
A-beta fibers
Quickly adapting
No sustained discharge if hair is bent for more than a few seconds
Slowly adapting
Discharge for the duration of the stimulus
Maintained events
Free nerve endings
Nociceptors that detect pain
Subspecialized, myelinated and unmyelinated
A-delta fibers in skin and mucosa
Cuneate fasiculus
Added lateral and gracile fascicles at ind-thoracic cord level
Transmits input from upper trunk, arms, and neck
Dorsal column senses
light/fine touch, proprioception of trunk and limbs
Internal arcuate fibers
Axons from cells in dorsal column nuclei
Cross to other side of brainstem and form medial lemniscus
Rapidly adapting
Discharges briefly then stops
Potentials at start and end of stimulus
Transient or high frequency events
I-a fibers
Fast conduction axons involved in muscle stretch, primarily spindle receptors in proprioception
A-delta fibers
Large diameter, conduct slightly slower than A-beta
Touch, temperature, and pain
A-beta fibers
Large diameter, more rapidly conducting axons
Supply majority of touch receptors
Ventral quadrant senses
pain, temperature, crude touch
Motor pathways
Motor nucleus of V -> motor neurons to muscles of mastication
Trigeminal nerve -> muscles of mastication
Somesthesis
body sensibility or somatosensory capacities
Interoceptors
located within the viscera and respond to changes in internal environment
Merkel cells
slowly adapting touch receptors located in hairy skin in face, glabrous skin of hand
Dorsal column pathway (forelimb and cranial trunk)
DRGC -> cuneate fasiculus -> synapse in cuneate fasiculus -> cross as internal arcuate fibers -> medial lemniscus -> VCL -> internal capsule -> somatosensory cortex
Face somesthetic pathway (light touch)
Trigeminal ganglion cells -> trigeminal nerve -> prinicpal/chief sensory nucleus -> joins medial lemniscus -> VCM -> somatosensory cortex
Face somesthetic pathway (proprioception from muscles of mastication)
Mesencephalic nucleus -> spinal tract of V -> trigeminal nerve -> muscles of mastication
Mesencephalic nucleus cells have peripheral processes in muscle proprioceptors, cell bodies in mesencephalon, and central processes terminating in motor nucleus of V
Face somesthetic pathway (crude touch, pain, temp)
Trigeminal ganglion cells -> spinal trigeminal tract -> spinal trigeminal nucleus then:
a. crossed spinothalamic tract -> VCM -> internal capsule -> somatosensory cortex
b. crossed spinoreticulothalamic tract -> reticular formation, IL, hypothalamus -> IL to internal capsule -> widespread cortical areas
c. some cross and join medial lemniscus -> VCM -> somatosensory cortex
Dorsal column pathway (hindlimb and caudal trunk)
DRGC -> gracile fasiculus -> synapse in gracile nucleus -> cross as internal arcuate fibers -> medial lemniscus -> VCL -> internal capsule -> somatosensory cortex
Ventral quadrant pathways
DRGC -> dorsal horn cells -> crossed spinothalamic tract -> VCL -> internal capsule -> somatosensory cortex
DRGC -> dorsal horn cells -> crossed spinoreticulthalamic tract -> reticular formation, IL, hypothalamus -> IL to internal capsule -> widespread cortical areas
What tracts compose the dorsal columns?
gracile fasciculus and cuneate fasciculus
Which tract serves the upper limbs?
cuneate fasciculus
Which tract serves the lower limbs?
gracile fasciculus
Where do the fibers which form the dorsal column tracts have their cell bodies? Do they arise/project ipsi or contra?
Soma are in the dorsal root and fibers arise ipsi.
No synapse in the dorsal horn
Are the dorsal column tracts arise with large or small fiber input?
large
What modalities are carried in the dorsal columns?
muscle, joint, hair, and touch receptors
Where do dorsal column tracts terminate?
cuneate and gracile nuclei (respectively)
Where does the medial lemniscus originate? Do these fibers arise on the ipsi or contra side?
Axons from the dorsal column nuclei (gracile/cuneate) cross (contra) and form the medial lemniscus
What modalities are carried by the medial lemniscus?
Direction of movement across skin Differentiation of tactile sensation Posture/dexterity of extremities Skin localization Shapes and textures Foot adapting m. Joint, hair, touch receptors
What body regions are represented in the medial lemniscus?
entire body
Where does the medial lemniscus terminate?
VCL thalamic nucleus
Tracts composing the ventral ascending pathways?
Spinothalamic and spinoreticular tracts (ST, SR)
Do these tracts carry modalities around with large or small peripheral afferent input?
small
What modalities do the ventral tracts carry?
pain, temperature and touch (PTT)
Where do the fibers that comprise the tracts have their cell bodies?
Spinal dorsal horn
Do these cells ascend ipsi or contra?
bilateral
Where do the SR tacts fibers terminate?
medullary reticular formation, IL complex, hypothalamus
Where do the ST tract fibers terminate?
VC thalamus and IL
How are the SR and ST tracts similar/different?
Modality: PTT (same)
Origin: spinal dorsal horn (same)
Course: SR- bi, ST- contra
Terminate: SR- IL, ST- VCL
Sensory modalities of the trigeminal nerve? Where are the cell bodies?
Face: PTT, cell bodies are in the trigeminal ganglion
What is the spinal tract of V?
the central process of the trigeminal ganglion which disperses input to all levels of the trigeminal complex
Where are the cells of origin of the ST of V?
trigeminal ganglion
Where does the ST of V terminate?
sensory nucleus and spinal nucleus of V
Which trigeminal nucleus is a/w transmittance of light touch?
chief sensory nucleus of V
How is proprioception transmitted to the cerebral cortex?
mesencephalic nucleus of V
Pain to the cerebral cortex?
subnucleus caudalis of spinal nucleus V
The primary cortex is in the:
posterior postcruciate gyrus
the foot is:
more medial compared to the face (on the gyrus)
difference in projection pattern: VCL/VCM/IL
VCL: specific
VCM: specific
IL: diffuse
What is the IL nucleus? What does it receive and where does it project?
IL nucleus: intralaminar nucleus of the thalamus
Receive: SR and ST tracts
Projects diffusely to cortex and other brain regions