somatosensory II Flashcards
fast pain receptor
mechanical and thermal nocioceptors
fast pain fiber type
small myelinated
fast pain tracts
neospinothalamic
fast pain thalamus
lateral VPL
fast pain function
sharp localized pain
slow pain receptor
polymodal nocioceptors
slow pain fiber type
unmyelinated
slow pain tracts
paleospinothalamic
spinoreticulothalamic
slow pain thalamus
medial thalamus
slow pain cortex
frontal and limbic
slow pain function
cortical arousal, affect
nociception proteases
breakdown kininogen to bradykinin
bradykinin bind to receptors that activate ion channels
heat over ___ opens heat sensitive ion channels on nociceptors
43
oxygen deprivation-
anaerobic metabolism release
lactic acid
–> high levels of H
polymodal
mechanical, thermal, chemical stimuli
capsaicin activates
TRPV1 receptor
trpv1 channels open at
lower temps