somatosensory II Flashcards

1
Q

fast pain receptor

A

mechanical and thermal nocioceptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

fast pain fiber type

A

small myelinated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

fast pain tracts

A

neospinothalamic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

fast pain thalamus

A

lateral VPL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

fast pain function

A

sharp localized pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

slow pain receptor

A

polymodal nocioceptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

slow pain fiber type

A

unmyelinated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

slow pain tracts

A

paleospinothalamic

spinoreticulothalamic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

slow pain thalamus

A

medial thalamus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

slow pain cortex

A

frontal and limbic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

slow pain function

A

cortical arousal, affect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

nociception proteases

A

breakdown kininogen to bradykinin

bradykinin bind to receptors that activate ion channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

heat over ___ opens heat sensitive ion channels on nociceptors

A

43

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

oxygen deprivation-

anaerobic metabolism release

A

lactic acid

–> high levels of H

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

polymodal

A

mechanical, thermal, chemical stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

capsaicin activates

A

TRPV1 receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

trpv1 channels open at

A

lower temps

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

aspirin inhibits enzymes for ____ synthesis

A

prostaglandin

19
Q

what fibers for pain and temp, some touch

A

A-delta(III)

small, thinly myelinated

20
Q

what fibers for slow pain and temp

A

C(IV)

21
Q

ascending pathways important for

A

position of body in space

arousal

22
Q

anterolateral system or spinothalamic pathway

A

pain temp itch touch

23
Q

pain fibers enter dorsal root enter zone ___

A

laterally

24
Q

dorsal root entry zone also known as

A

zone of lissauer

25
Q

second order neurons ascend contralaterally in the

A

medulla
pons
midbrain

26
Q

second order neurons synapse in

A

thalamus

27
Q

neospinothalamics synapse in

A

VP nucleus

28
Q

spinoreticular tract is information

A

to the reticular nuclei which project to intralaminar nuclei of thalamus
important in arousal

29
Q

spinomesencephalic tract information to

A

midbrain tectum
-coordinates eye and head movements
periaqueductal gray matter
-pain regulation

30
Q

dorsal column medial lemniscus for

A

vibration, proprioception, fine touch

31
Q

anteral lateral pathways for

A

pain, temp, crude touch

32
Q

in spinal cord ALS and DC-ML pathways on what sides

A

opposite

33
Q

ALS and DCML pathways come together in

A

caudal medulla

34
Q

with hemisection of spinal cord patient loses

A

pain from opposite side of body about 2 levels below lesion

touch etc on same side

35
Q

spinomesencephalic tract projects to

A

superior colliculus orienting to pain stimulus

periaqueductal gray-pain modulation

36
Q

thalamus projects to

A

primary somatic sensory cortex

37
Q

posterior thalamic nuclei
input
projects to

A

ALS

insular cortex

38
Q

medial dorsal nucleus
input
projection

A

ALS

anterior cingulate cortex and orbitofrontal

39
Q

thalamus plays role in

A

affecttive and motivational aspects of pain and in memory fo painful stimuli

40
Q

cortex for painful stimuli

A

insular cortex and anterior cingulate

41
Q

cortical projections from layers 5/6 project to

and modulate…

A

thalamus
brainstem
spinal cord

modulate sensory info thats ascending

42
Q

pain modulation from___ to ___

A

periaqueductal gray

nucleus raphe magnus

43
Q

neurons in raphe magnus project to

excite..

A

spinal cord
excite interneurons
-enkephalinergic
-inhibits 1st and 2nd order pain neurons

44
Q

neurons in locus cereleus are

A

noradrenergic