Solving pH and pKa Flashcards
How would you describe the Ka and pKa of a strong acid?
large Ka
small pKa
pKa is affected by ?
steric and electronic factors
when pH = pKa
[base form] = [acid form]
when pH < pKa
functional group is in an acidic environment with lots of protons
when pH > pKa
the functional group is in a basic environment with minimal protons
If the functional group is the same as its environment it will be primarily ?
unionized
If a functional group is different from its environment it will be primarily ?
ionized
lpH - pKal = 0
50:50 ratio between ionized and unionized forms
lpH - pKal = 1
there’s a 90:10 ratio between ionized and unionized forms
lpH - pKal = 2
there’s a 99:1 ratio between ionized and unionized forms
lpH - pKal = 3
there’s a 99.9:0.1 ratio between ionized and unionized forms
lpH - pKal = 4
there’s a 99.99:0.01 ratio between ionized and unionized forms