Soluble Oxalate poisoning Flashcards

1
Q

What plants contain large amounts of soluble oxalates? (cattle and sheep)

A
Pigweed
Halogeton
Greasewood
Lamb's quarters
Sorrel, sour sob
Sorrel, dock
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2
Q

Sheep may be poisoned by ____ of body weight with soluble oxalates

A

0.55%

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3
Q

Starved sheep or water deprived can be killed by only ___ of body weight with soluble oxalates

A

0.1%

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4
Q

What plant contains 3 toxins, Soluble oxalates, nitrates and an unknown toxin that causes renal disease?

A

Pigweed (Amaranthus retroflexus)

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5
Q

What is the nonfatal toxic dose to adult horses of soluble oxalate?

A

200g/day for 8 days

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6
Q

What species are more susceptible to soluble oxalates?

A

Sheep and cattle (although the rumen microflora can detoxify oxalates to carbonates and bicarbonates)

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7
Q

Ruminants allowed to graze small quantities of oxalate containing plants gradually results in detoxification of up to ____ soluble oxalates than normal

A

70%

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8
Q

What plant parts contain the highest amount of soluble oxalates?

A

Leaves > seeds > stems

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9
Q

T/F. Short amount of soluble oxalates over a long period is more toxic

A

False - large amount over short period is more toxic

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10
Q

What could reduce the rate of soluble oxalate absorption?

A

food in the rumen

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11
Q

What could decrease toxicity of soluble oxalates by forming insoluble compounds that are not absorbed?

A

Calcium or calcium rich diet - form insoluble calcium oxalate

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12
Q

What could increase the oxalate content of some forages?

A

Oxalate producing fungi - in moldy forages

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13
Q

What animal is more susceptible to soluble oxalate and which one is more susceptible to nitrate and cyanide?

A

Sheep - soluble oxalate

Cattle - nitrate and cyanide

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14
Q

What was the most toxic part in the plant to nitrate? Cyanide? Soluble oxalate?

A

Nitrate - stalk
Cyanide - seed
Soluble oxalate - leaf

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15
Q

Once soluble oxalates are absorbed, they combine with calcium ion to form insoluble calcium oxalates, what does that lead to?

A

hypocalcemia and tetany in acute cases or affects bone and milk production in lower levels

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16
Q

What do the calcium oxalate crystals cause in the kidney?

A

Precipitation of calcium oxalate crystals in the kidney tubules cause kidney damage and necrosis

17
Q

What clinical signs will you see with soluble oxalate poisoning?

A

Colic, dullness, depression, muscle twitching, muscle weakness, neck pulled to one side, coma, death
Rapid breathing and blood tinged froth around the mouth
COnvulsions

18
Q

What laboratory diagnosis could confirm soluble oxalate poisoning?

A

Hypocalcemia

High BUN

19
Q

How could you tell the difference between rumen acidosis and soluble oxalate poisoning?

A

The rumen pH in oxalate is alkaline