sodium Flashcards
Sodium is
main cation of ECF
Function of sodium
generation and transmission of nerve impulse, muscle contractility, and regulation of acid base balance
how does sodium leave the body?
urine, sweat, and feces
what is the primary regulator of sodium balance
kidneys
how does the kidneys regulate the ECF concentration of sodium
by excreting/retaining water under the influence of ADH
What does Aldosterone do?
regulates sodium by promoting sodium reabsorption from renal tubule
serum sodium levels reflect
ratio of sodium to water
change in serum sodium levels can reflect
water and sodium imbalance
Sodium Labs
135-145 mEq/L
Hypernatremia- Pts who are at risk
(high sodium)
water loss/sodium gain
causes hyperosmolality
what is hyperosmolality?
shift of water out of the cells (cellular dehydration)
Hypernatremia- what does sodium retention cause?
RF
Hypernatremia- how to get sodium
OTC meds, dietary sodium, corticosteroids
Hypernatremia- water loss
water deprivation: cognitive impairment= pt cant communicate their needs
diabetes insipidus: problems with ADH (synthesis/release); causes diuresis (inc urine)
Hypernatremia- CNS
early: restless, agitation, muscle twitch, dec alertness
later/severe: lethargy, weakness, dec DTRs (assess pt’s level of skeletal muscle strength)
as sodium inc (muscle and nerve controlled by sodium) less likely to respond to stimulus (severe)
Hypernatremia- CV
dec contractility