Smooth muscles drugs Flashcards
What type of muscles do drugs that act on smooth muscles primarily target?
Smooth muscles in various organs.
True or False: Smooth muscle drugs can only be used in the gastrointestinal tract.
False.
Name a class of drugs that relax smooth muscles.
Antispasmodics.
Fill in the blank: __________ is a common smooth muscle relaxant used in asthma treatment.
Albuterol.
What is the primary action of calcium channel blockers on smooth muscles?
They inhibit calcium influx, leading to relaxation of smooth muscle.
Which drug is known as a non-selective beta-agonist that affects smooth muscle?
Isoproterenol.
True or False: Nitric oxide is a signaling molecule that causes smooth muscle contraction.
False.
What is the mechanism of action of sildenafil in relation to smooth muscles?
It inhibits phosphodiesterase-5, increasing cGMP levels and causing relaxation.
What type of receptor do smooth muscle relaxants typically act on?
Beta-adrenergic receptors.
Fill in the blank: __________ are drugs that can induce uterine smooth muscle contraction.
Oxytocin.
Which drug is commonly used to treat hypertension by relaxing vascular smooth muscle?
Amlodipine.
True or False: Smooth muscle contraction is primarily regulated by the nervous system.
True.
What is the role of prostaglandins in smooth muscle function?
They can either stimulate contraction or relaxation depending on the type.
Name a smooth muscle relaxant used to treat overactive bladder.
Oxybutynin.
Which type of smooth muscle is primarily found in the walls of hollow organs?
Visceral smooth muscle.
Fill in the blank: __________ is a drug that acts specifically on the smooth muscle of the airways.
Ipratropium.
What is the effect of atropine on smooth muscle?
It inhibits parasympathetic activity, leading to relaxation.
True or False: All smooth muscle relaxants are also vasodilators.
False.
What is the primary therapeutic use of smooth muscle relaxants?
To relieve spasms and reduce pain.
Name a smooth muscle agonist that can cause vasodilation.
Nitroglycerin.
What physiological process do smooth muscle drugs often influence?
Vascular tone and motility of hollow organs.
Fill in the blank: __________ is a calcium sensitizer that enhances smooth muscle contraction.
Levosimendan.
What is the role of cyclic AMP in smooth muscle relaxation?
It promotes relaxation by inhibiting myosin light chain kinase.
Which drug is often used to manage chronic obstructive pulmonary disease (COPD) by acting on smooth muscles?
Tiotropium.
True or False: Smooth muscle contraction is involuntary and controlled by the autonomic nervous system.
True.
