Autonomic Pharmacology Flashcards
What is the primary neurotransmitter of the sympathetic nervous system?
Norepinephrine
True or False: The parasympathetic nervous system is primarily responsible for ‘fight or flight’ responses.
False
Fill in the blank: The drug ___ is a selective beta-1 adrenergic agonist used primarily in cardiac applications.
dobutamine
What type of receptor does acetylcholine bind to in the autonomic nervous system?
Cholinergic receptors
Which class of drugs is used to block the effects of acetylcholine?
Anticholinergics
What is the main effect of alpha-1 adrenergic receptor activation?
Vasoconstriction
True or False: Atropine is an example of a beta-adrenergic antagonist.
False
What is the mechanism of action of beta-blockers?
They block beta-adrenergic receptors.
Which drug is commonly used to treat asthma by acting as a beta-2 agonist?
Albuterol
Fill in the blank: The enzyme that breaks down acetylcholine is called ___.
acetylcholinesterase
What is the primary effect of parasympathetic stimulation on heart rate?
Decreases heart rate
True or False: Epinephrine can activate both alpha and beta adrenergic receptors.
True
What is the primary therapeutic use of anticholinergic drugs?
To reduce secretions and treat bradycardia
Which adrenergic receptor subtype is primarily involved in smooth muscle relaxation?
Beta-2 receptors
Fill in the blank: The drug ___ is used to treat hypertension by acting as an alpha-2 agonist.
clonidine
What is the effect of cholinergic agonists on pupil size?
Miosis (pupil constriction)
True or False: Beta-1 receptors are primarily located in the lungs.
False
What type of drug is used to reverse the effects of neuromuscular blockers?
Cholinesterase inhibitors
Which condition is commonly treated with beta-blockers?
Hypertension
Fill in the blank: The primary neurotransmitter at the neuromuscular junction is ___.
acetylcholine
What is the role of the sympathetic nervous system in the body?
To prepare the body for ‘fight or flight’ response.
Which drug is known as a non-selective beta blocker?
Propranolol
True or False: Dopamine can act on both adrenergic and dopaminergic receptors.
True
What is the primary effect of beta-1 receptor activation in the heart?
Increases heart rate and contractility
Fill in the blank: The drug ___ is an anticholinergic used to treat motion sickness.
scopolamine
What is the primary function of the autonomic nervous system?
To regulate involuntary physiological functions.
Which neurotransmitter is released by postganglionic sympathetic neurons?
Norepinephrine