Small / Large for Gestational Age Flashcards
What is meant by small for gestational age (SGA)?
when a fetus measures below the 10th centile for their gestational age
What ultrasound measurements are used to assess fetal size?
- estimated fetal weight (EFW)
- fetal abdominal circumference (AC)
(abdominal circumference is always measured at the level of T12)
What ultrasound measurements can be used to calculate EFW?
- biparietal diameter (BPD)
- head circumference (HC)
- abdominal circumference (AC)
- femur length (FL)
What is used to assess the size of the fetus?
customised growth charts
- these are based on the mother’s weight, height, parity + ethnic group
What is severe SGA?
when the fetus is below the third centile for their gestational age
What is a low birth weight?
birth weight of less than 2500g
How is fetal growth monitored on a customised growth chart?
- both symphysis-fundal height** and **estimated weight by scan are plotted on the chart
- growth can be compared to the decile lines
- and any plateau in growth can be detected
What are the 2 categories of causes of SGA?
constitutionally small:
- the fetus is small in size but matches the mother / others in the family
- it is growing appropriately on the growth chart
fetal growth restriction (IUGR):
- there is a small fetus or one that is not growing as expected
- this is due to pathology reducing the delivery of oxygen / nutrients to the fetus through the placenta
What are the 2 categories of causes of intrauterine growth restriction?
(IUGR = FGR)
- placenta mediated growth restriction
-
non-placenta mediated growth restriction
- small due to genetic / structural abnormality
What causes placenta mediated growth restriction?
conditions that affect the transfer of nutrients across the placenta:
- pre-eclampsia
- maternal smoking / alcohol
- anaemia
- malnutrition
- infection
- maternal health conditions
- idiopathic
What causes non-placenta mediated growth restriction?
pathology of the fetus, such as:
- genetic abnormalities
- structural abnormalities
- fetal infection
- errors of metabolism
Other than SGR, what other factors can suggest IUGR?
- reduced amniotic fluid volume
- abnormal doppler studies
- reduced fetal movements
- abnormal CTGs
What are the short-term complications of IUGR?
- fetal death / stillbirth
- birth asphyxia
- neonatal hypothermia
- neonatal hypoglycaemia
What are the long-term implications for growth-restricted babies?
- cardiovascular disease (particularly hypertension)
- diabetes
- obesity
- mood / behavioural problems
What are the modifiable risk factors for SGA?
- obesity
- smoking
- diabetes
- existing hypertension