Small Intestines Flashcards
What are the general functions of the small intestines?
Digestion
Absorb Nutrients
Produce Intestinal Hormones using DNES cells
What are the 3 surface adaptations to increase surface area by a factor of 400+?
Plicae Circulares
Villi
Microvilli
What are permanent folds affecting the mucosa and submucosa and are also found together throughout the duodenum, jejunum and proximal ileum?
Plicae Circulares
What surface adaptation is found on the luminal cell surface?
Microvilli
What is the surface epithelium for the mucosa of the small intestine?
Simple Columnar
What are the cell types found in the surface epithelium of the small intestine?
Surface Absorptive Cells Goblet Cells DNES Cells Regenerative Cells Paneth Cells M Cells
What is another name for surface absorptive cells?
Enterocytes
What are the main functions of the surface absorptive cells?
Absorb Water and Nutrients
Terminal DIgestion in Glycocalyx
Which cell is found least in the duodenum but mostly in the ileum?
Goblet Cells
Type I DNES cells produce what that will stimulate gallbladder contraction and pancreatic secretion of enzymes from serous acini?
CCK
Type K DNES cells produce GIP which inhibits?
HCL release
Type S DNES cells produce what that stimulates pancreas secretion of bicarbonate from the pancreatic ducts. It will also inhibit HCL release and the movement of chyme into small intestines?
Secretin
How long do paneth cells live?
About 20 days
What is the location of paneth cells?
Crypts (intestinal glands)
What is the function of paneth cells?
Lysozymes
What is the location of M cells?
Ileum epithelium over peyers patches
What cells contain large intracellular pockets that are fairly open to the lamina propria?
M cells
M cells sample foreign antigens in gut lumen and transfer antigens to lymphocytes and dendritic cells that have entered the?
M cell pockets
What is the function of M cells?
Promote Humoral Immunity