Liver Flashcards
What is the largest gland in the body with endocrine and exocrine functions?
Liver
What are the general functions of the liver?
Metabolism of lipids, carbs, proteins Production of blood proteins, factors and non-essential vitamins Detoxify Blood Produce Hepatic Bile (exocrine) Store Vitamine (A, B12)
What cells are microvilliated cubodial cells possessing lateral bile canalinuli between adjacent hepatocytes?
Hepatocytes
What collects bile in the liver?
Bile Canaliculi
Bile moves from the hepatocytes towards the bile duct branch in the ?
Portal Triad
What cells are found in the liver?
Hepatocytes Kupffer Cells Ito Cells (hepatic stellate) Pit Cells Hepatic Progenitor Cells
What cells are resident macrophages the develop from monocytes?
Kupffer Cells
What is the function of kupffer cells?
Phagocytosis of debris and aged RBC’s
Act as an APC
What is the function of Ito cells?
Store lipids for immediate use
Store Vit A
Produce Collegen I, III, IV and growth factors
What cells are natural killer cells?
Pit Cells
What cells are likely present and responsible for regenerative capabilities?
Hepativ Progenitor Cells
The portal triad includes branches of the?
Hepatic A
Portal V
Bile Duct
Lymph Vessels
What are dilated, fenesterated thin walled vessels found between the rows of hepatocytes that carry a mixture of venous and arterial blood?
Hepatic Sinusoids
What is a fenesterated thin walled vessel that collects blood from hepatic sinusoids?
Central V
Blood flows from the portal triad to the?
Central V
The space of disse is also called?
Perisinusoidal Space
The space of disuse is a space between the hepatocytes and fenesterate hepatic sinusoids where blodd can directly contact what?
Microvilliated surfaces of hepatocytes
What is the reason the liver can take over functioning for the spleen in 24-48 hours?
Space of disse allows blood to flow slow enough that cells can interact with blood and contents.
What is glisson’s capsule composed of?
Dense Irregular CT covered with serosa
