Liver Flashcards

1
Q

What is the largest gland in the body with endocrine and exocrine functions?

A

Liver

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2
Q

What are the general functions of the liver?

A
Metabolism of lipids, carbs, proteins
Production of blood proteins, factors and non-essential vitamins
Detoxify Blood
Produce Hepatic Bile (exocrine)
Store Vitamine (A, B12)
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3
Q

What cells are microvilliated cubodial cells possessing lateral bile canalinuli between adjacent hepatocytes?

A

Hepatocytes

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4
Q

What collects bile in the liver?

A

Bile Canaliculi

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5
Q

Bile moves from the hepatocytes towards the bile duct branch in the ?

A

Portal Triad

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6
Q

What cells are found in the liver?

A
Hepatocytes
Kupffer Cells
Ito Cells (hepatic stellate)
Pit Cells
Hepatic Progenitor Cells
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7
Q

What cells are resident macrophages the develop from monocytes?

A

Kupffer Cells

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8
Q

What is the function of kupffer cells?

A

Phagocytosis of debris and aged RBC’s

Act as an APC

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9
Q

What is the function of Ito cells?

A

Store lipids for immediate use
Store Vit A
Produce Collegen I, III, IV and growth factors

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10
Q

What cells are natural killer cells?

A

Pit Cells

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11
Q

What cells are likely present and responsible for regenerative capabilities?

A

Hepativ Progenitor Cells

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12
Q

The portal triad includes branches of the?

A

Hepatic A
Portal V
Bile Duct
Lymph Vessels

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13
Q

What are dilated, fenesterated thin walled vessels found between the rows of hepatocytes that carry a mixture of venous and arterial blood?

A

Hepatic Sinusoids

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14
Q

What is a fenesterated thin walled vessel that collects blood from hepatic sinusoids?

A

Central V

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15
Q

Blood flows from the portal triad to the?

A

Central V

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16
Q

The space of disse is also called?

A

Perisinusoidal Space

17
Q

The space of disuse is a space between the hepatocytes and fenesterate hepatic sinusoids where blodd can directly contact what?

A

Microvilliated surfaces of hepatocytes

18
Q

What is the reason the liver can take over functioning for the spleen in 24-48 hours?

A

Space of disse allows blood to flow slow enough that cells can interact with blood and contents.

19
Q

What is glisson’s capsule composed of?

A

Dense Irregular CT covered with serosa