Clinical Aspects

Question 1

What are the 2 general causes of peptic ulcer disease?

Answer 1

Insufficient protection from HCL and Pepsin

Helicobacter Pylori

Question 2

Insufficient protection from HCL and pepsin causes what?

Answer 2

Damaged Mucus Coat

Too much HCL and Pepsin

Question 3

If luminal acidity is decreased, damaged tissues can repair in?

Answer 3

1-2 Months

Question 4

What are some factors that delay healing of a peptic ulcer?

Answer 4

Cigarette Smoking
Alcohol
Caffiene
Calcium
Aspirin

Question 5

What is the name of the disease where stomach chyme backs up into lower esophagus?

Answer 5

Gastroesophageal Reflux

Question 6

What are the possible contributing factors for gastroesophageal reflux?

Answer 6

Chronic Gastritis
Hiatal Hernia
Pregnancy
Incompetent Lower Esophageal Sphincter
Subluxations

Question 7

What are some ways to reduce reflux?

Answer 7

Food Diary
Limit how much is eaten at one time
Don’t eat less than 3 hrs before bed

Question 8

What are some problem foods for reflux?

Answer 8

Spices
Acidic Foods
Acidic Beverages
Fatty Foods
Alcohol

Question 9

What is the disease where stratified squamous epithelium is replaced by mucus secreting simple columnar in the lower esophagus?

Answer 9

Barrett’s Esophagus

Question 10

Barrett’s esophagus is metaplasia due to?

Answer 10

Chronic Problem