Small Group 7 Allergies

Question 1

Discuss the sequence of events for development of an allergic reaction. (IgE)

Answer 1

exposure to allergen
production of allergen specific IgE
IgE binds FceRI on mast cells
re-exposure to allergen
IgE cross linking
mast cell degranulation

Question 2

What mediator is most responsible for sneezing an prutis in allergic rhino conjunctivitis?

Answer 2

histamine

Question 3

Describe the step wise approach to treatment of allergic rhinitis.

Answer 3

avoidance
anti-histamine
nasal coriticostroids
allergy immunotherapy

Question 4

What is the dose and route of medication to treat anaphylaxis?

Answer 4

epinephrine 0.3mg IM for an adult, can be administered every 5min as needed

Question 5

Presentation of treatment of sinus infection with amoxicillin with generalize hives, fever and painful swelling of the knees and ankles is likely what type of hypersensitivity reaction?

Answer 5

Type III- immune complex reaction

note future reactions to this drug can be more severe with quicker onset

Question 6

What is the rule of two?

Answer 6

controller medication should be used for someone suffering asthma if they have daytime symptoms more than twice a week and nocturnal symptoms more than twice per month