Small animal vaccination and pet travel Flashcards
What are the reasons to vaccinate?
- Responsible pet ownership – annually, get a full health check up
- Having an annual check up with a vet means we can spot other clinical disease earlier
- Maintains a healthy pet population
- Reduces deaths
- Reduces incidence of zoonoses
- Validates insurance policies
How are maternally derived antibodies derived?
From the dam via colostrum
What is the importance of maternally derived antibodies?
Passive transfer of maternal immunoglobulins is VITAL for protection of the neonate against respiratory, enteric and systemic infection
How do maternally derived antibodies affect vaccination?
- MDA inhibit the development neonatal immunoglobulins until the maternally-derived antibodies have been degraded
- A neonates’ immune system cannot respond effectively to vaccination until MDAs have waned off (can take several months)
What are the 3 types of vaccine?
- Modified live
- Killed
- Recombinant
Describe each of the 3 types of vaccine
- Modified live: contain a virus that has been modified to lose its disease-causing ability (attenuation)
- Killed: attenuated through a process that results in their death
- Recombinant: part of the genetic sequence of the virus/bacterium are isolated that encode immunogenic proteins in patients
Give an examples of each of the 3 vaccine types
- Modified live = smallpox
- Killed = L4
- Recombinant = FeLV
What are the BSAVA’s 4 canine core vaccines?
- Distemper
- Hepatitis
- Parvovirus
- Leptospirosis
Describe the features of canine distemper virus including:
- Route of infection
- Incubation period
- Clinical signs
ROI = inhalation
Incubation = 3-10 days
Clinical signs:
- Respiratory, alimentary, oculo-nasal signs 2 wks post infection
- Neurological signs 4 wks post infection
- Hyperkeratosis of nose and foot pads around 3 months post infection
Canine infectious hepatitis is caused by which virus?
Canine adenovirus 1
Canine adenovirus 2 is associated with?
Respiratory disease (Kennel cough complex)
Describe the features of canine infectious hepatitis including:
- Route of infection
- Dogs affected
- Clinical signs
ROI = saliva, faeces, urine
Affects dogs less than 6 months old
Clinical signs:
- ‘blue eye’ (20% of cases), pyrexia, lethargy, cranial abdominal pain, V/D
Describe the features of canine parvovirus including:
- Route of infection
- Incubation period
- Clinical signs
ROI = Faeco-oral (HIGHLY INFECTIOUS)
Incubation = 4-7 days
Clinical signs:
- lethargy, vomiting, profuse diarrhoea (haemorrhagic)
How can canine parvovirus be efficiently diagnosed?
Faecal snap - result in 8 minutes
How do positive cases of canine parvovirus need to be treated?
Isolation, intense medical support
Leptospirosis has the zoonotic potential to cause which disease in human?
Weil’s disease
Where are leptiosprires secreted from?
Rodent urine and can then survive in water for months
Describe the features of Leptospirosis including:
- Route of infection
- Clinical signs
ROI = ingestion of infected urine from dog or rat or rat bites
Clinical signs:
- Vary from subacute ⟺ renal/hepatic damage depending on serovar and host immunity
- Acute/subacute jaundice, haemorrhagic syndrome, uraemic syndrome, chronic active hepatitis
How is leptospirosis diagnosed and treated?
Diagnosis - clinical signs, culture/microscopy from blood/urine/tissue, MAT, PCR, ELISA (SNAP)
- Treatment: supportive and IV penicillins
Describe the lepto-2 vaccine and its dosing
- Active immunization of dogs against 2 strains of leptospira
- Interval of 2-4 weeks between 1st and 2nd vaccination
What is the main benefit of lepto-2 vaccine?
Allows early puppy socialisation due to short dosing interval
Describe the lepto-4 vaccine and its dosing
- Active immunization of dogs against 4 strains of leptospira
- Interval of 4 weeks between 1st and 2nd vaccination