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Neuro Week 3 > Sleep Disorders > Flashcards

Sleep Disorders Flashcards

1
Q

where does the suprachiasmatic nucleus receive direct input?

A

retina

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2
Q

what does the SCN control secretion of?

A

melatonin

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3
Q

what are two types of sleep?

A

NREM and REM

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4
Q

how many stages of NREM?

A

4

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5
Q

what is sleep cycle order?

A

NREM 1,2,3,4 then REM

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6
Q

does REM increase or decrease through the night?

A

increase

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7
Q

NREM 1 is what wave?

A

theta

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8
Q

NREM 2 has what on EEG/

A

sleep spindles and K complexes

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9
Q

NREM 3 is what wave?

A

delta

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10
Q

REM sleep is what wave?

A

beta wave

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11
Q

what happens in NREM 3?

A

sleepwalking/night terrors/bed wetting

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12
Q

what happens in REM?

A

muscle tone loss..dreams

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13
Q

awake with eyes closed has what waves?

A

alpha waves

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14
Q

totally awake has what waves?

A

beta waves

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15
Q

what is most common sleep disorder?

A

insomnia

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16
Q

how long must you have difficulty staying or falling asleep for insomni?

A

over 1 month

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17
Q

what are three common comorbidities with insomnia?

A

mood disorders
anxiety
pain

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18
Q

what happens in narcolepsy?

A

drop into REM sleep during wakefulness

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19
Q

what are the four main features of narcolepsy?

A

excess sleepiness, cataplexy
sleep paralysis
hypnogogic hallucination

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20
Q

what is sleep paralysis?

A

mind awake but unable to move

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21
Q

what is at onset of sleep study in narcolepsy?

A

REM sleep

22
Q

what is restless leg syndrome?

A

urge to move legs with uncomfortable crawling sensations

23
Q

when does RLS most commonly occur?

A

evening at night

24
Q

what is RLS treated with?

A

dopamine agonist

25
Q

what is RLS associated with?

A

iron deficiency anemia

26
Q

what happens in the REM sleep disorder

A

loss of normal skeletal muscle atonia…

27
Q

what does person do in REM sleep behavior disorder since they lost their normal skeletal muscle atonia?

A

they act out dreams

28
Q

when do night terrors occur in sleep?

A

stage 3/4

29
Q

who gets night terrors

A

children

30
Q

how long do night terrors last?

A

10 minutes

31
Q

what is a night terror?

A

unexplained bouts of terror/fear about 70 minutes into sleep

32
Q

can you awake a child having night terror?

A

no

33
Q

when does sleep wlalking occur in sleep?

A

stage 3/4

34
Q

who gets sleep walking?

A

children mainly

35
Q

do you have memor/y of sleep walking

A

no you dont

36
Q

what is bruxism?

A

grinding of the teeth during sleep

37
Q

when does bruxism occur?

A

during sleep

38
Q

if problem is getting to sleep, what do we give for Rx?

A

a hypnotic

39
Q

if problem is getting to sleep, what do we give for Rx?

A

a hypnotic

40
Q

what are the three long acting Benzos?

A

temazepam
lorazepam
diazepam

41
Q

what are the four short acting benzos?

A

Alprazolam
Triazolam
Oxazepam
Midazolam

42
Q

what three benzos to give with liver failure?

A

Lorazepam
Oxazepam
Temazepam

43
Q

what is antidote of benzo?

A

flumazenil

44
Q

name the Z drugs

A

zolpidem
eszopiclone
zalpelon

45
Q

what is MoA of Z drugs?

A

bind to GABA a1 receptor that modulates sleep

46
Q

what are Z drugs antidote?

A

flumazenil too

47
Q

what is MoA of remelteon?

A

activated maltonin receptors in the suprhiasmatic nucleus of the hypothalamus

48
Q

what is ramelteon used for?

A

insomnia rx

49
Q

what is MoA of suvoxerant?

A

orexin receptor antagonist

50
Q

what is suvoxerant contraindicated in?

A

liver disease, narcolepsy

51
Q

what are the anti depressants commonly used for sedation side effect profile?

A

TCA and trazodone

Neuro Week 3 (13 decks)

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