Sleep Disorders

Question 0

What is the best treatment for narcolepsy with cataplexy

Answer 0

Sodium oxybate

Question 1

What is the treatment for advance sleep phase disorder

Answer 1

This is characterized by early sleep onset an early morning awakenings due to the shift in the circadian rhythm to the early part of the night. Treatment recommendations include exposure to bright lights in the evening and melatonin in the morning

Question 2

How many apnea/hypopnead are required to qualify for a diagnosis of obstructive sleep apnea

Answer 2

Five events per hour

Question 3

How many events per our qualified for a definition of periodic limb movement disorder

Answer 3

Greater than or equal to 15 events per hour

Question 4

What treatment can be considered in the treatment of Klein-Levin syndrome

Answer 4

This is a sleep disorder associated with recurrent hypersomnia as well as behavioral and cognitive changes can be treated with Lithium

Question 5

What are genetic findings and sleep study findings in patients with Narcolepsy with cataplexy

Answer 5

MS LT results should show I mean sleep latency less than eight minutes with at least to sleep onset REM periods. Primary etiology is felt to be due to low CSF hypocretin levels .it is felt that there is an autoimmune trigger I’m genetic testing shows patients positive for HLA-DQB1 0602 subtype