Critical Care And Trauma Flashcards

0
Q

How many days of AED drug prophylaxis is recommended after severe traumatic brain injury

A

7

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1
Q

When should Mechanical ventilators support be initiated in a myasthenia crisis

A

When FVC falls below 1 L and NIF is below 20 cm H2O.
Noninvasive mechanical ventilation using bilevel positive pressure ventilation, may circumvent the need for intubation if the pCO2 is > 50 mm Hg

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2
Q

What is the treatment for malignant MCA infarction which is typically associated with progressive cerebral Adema typically peaking at 2 to 5 days postinfarction

A

Hyperosmolar therapy with either mannitol (0.5 grams:kg IV) or hypertonic saline

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3
Q

Or what circumstances has therapeutic hypothermia been shown to improve the outcome

A

Out of hospital cardiac arrest and neonatal hypoxic ischemic encephalopathy

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4
Q

What enzyme is affected with hypothermia

A

Cytochrome P4 50 system enzyme activity is reduced up to 22% per degree below 37°C affecting metabolism and Clearence of sedative and neuromuscular blocking agents

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5
Q

What are the predictors of the more prolonged resolution of postconcussive symptoms

A

Duration of loss of consciousness, prior concussions, preexistent neuropsychiatric disorders such as depression anxiety or attentional disorders or prior history of migraine

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