sleep Flashcards
neurons in what nucleus generate the circadian rhythm?
suprachiasmatic
The protein products from what act as TF’s to increase period and crypto chrome?
BMAL1 and CLOCK
The transcription factors BMAL1 and clock act on what?
PERIOD and Cryptochrome
eyes opened or closed in alpha waves?
Closed
Where do alpha waves come from?
Occipital cortex
What is the amplitude and frequency of alpha waves?
High frequency, low amplitude
eyes opened or closed in beta waves?
Open
Where do beta waves come from?
Frontal, parietal cortex
Amplitude and frequency of beta waves?
High frequency, low amplitude
Are gamma wave fast or slow?
Slow
What are gamma waves associated with?
motor response
Theta waves are?
Slow, higher amplitude
When do theta waves appear? (3)
- ) frustration
- ) disappointment
- ) sleep
Delta waves are the?
Slowest, largest
What do delta waves represent?
Dissociation of the cortex and thalamus
What does alpha block or alerting response mean?
Eyes opened and changed to a B wave
What waves predominate in infants?
Beta waves
Changes in waves come from what 4 things?
- ) hypoglycemia
- ) decreased body temp
- ) decreased adrenal function
- ) Increased PaCO2
What is the EEG in REM?
Low amplitude, high frequency
Sleep induction involves?
PGD2 accumulation in the periphery. This leads to adenosine accumulation in the CSF.
Adenosine binds where?
Ventral Preoptic Region. VPO
VPO neurons inhibit what?
ARAS
REM sleep is induced by what neurotransmitter?
Ach
Where is Ach released?
Geniculate body
