Renal Shit I Dont Know

Question 1

What is B cell lymphoma associated with?

Answer 1

Membranoproliferative GN

Question 2

What does type I MPGN occur exclusively in?

Answer 2

Adults

Question 3

What else is MPGN I seen in?

Answer 3

Hep C, SLE, and malignancies

Question 4

What pattern does MPGN tend to be?

Answer 4

Nephritic and nephrotic

Question 5

What 3 things is MPGN I associated with?

Answer 5

1. ) SLE
2. ) Malignancies
3. ) Hep C

Question 6

What does type II MPGN activate?

Answer 6

alternative complement

Question 7

Describe the histo findings of MPGN

Answer 7

Mesangial proliferation with involvement of the BM

Question 8

LM of MPGN

Answer 8

Hypercellularity of the mesangium with a double contour and tram track appearance

Question 9

EM of MPGN

Answer 9

Subendothelial dense deposits

Question 10

IF of MPGN

Answer 10

Granular pattern with IgG, IgM, and C3

Question 11

What is secondary MPGN almost always?

Answer 11

Type I MPGN

Question 12

What is type II MPGN associated with?

Answer 12

C3NeF

Question 13

What is the morphology of type II MPGN?

Answer 13

mesangial proliferative pattern

Question 14

What is the EM of T2 MPGN?

Answer 14

electron dense ribbon of material

Question 15

What is the IF of T2 MPGN?

Answer 15

C3 present in irregular granular or linear foci