SLE Flashcards
1
Q
What are some differentials for SLE?
A
CTD
Vasculitis
Inflammatory arthritis
2
Q
What antibodies should be tested for in SLE?
A
ANA ENAs Anti dsDNA Anti-Smith Antiphospholipid
3
Q
What blood tests should be done for suspected SLE?
A
FBC U and E LFTs Clotting CRP ESR
4
Q
What are the 11 diagnostic criteria for SLE?
A
- Malar rash
- Discoid rash
- Photosensitivity
- Oral ulcers
- Arthritis (2 or more joints)
- Serositis
- Renal disorder
- Neurological disorder
- Haematological disorder
- ANA positive
- Immunologic disorder
Need 4 or more
5
Q
What constitutes serositis in SLE?
A
Pleuritis or pericarditis
6
Q
What constitutes a renal disorder in SLE?
A
Proteinuria or cellular casts
7
Q
What constitutes a neurological disorder in SLE?
A
Seizures or psychosis
8
Q
What constitutes a haematological disorder in SLE?
A
Anaemia
Thrombocytopenia
Leukopenia
9
Q
What constitutes an immunologic disorder in SLE?
A
Anti-Smith
Antiphospholipid
Anti dsDNA
