Skin manifestations of systemic disease Flashcards
Name two causes of erythema nodosum?
IBD, TB, sarcoidosis, oral contraceptives.
What are the symptoms of erythema nodosum?
pain blue/red bruise-like lesions on anterior shins
Which drugs can cause erythema multiforme?
SNAPP sulphonamides NSAIDs allopurinol (gout) penicillin phenytoin
Which skin manifestation is nearly always drug induced?
SJS/TEN
Name three diseases associated with pyoderma gangrenosum
IBD
RA
myeloma
leukaemia
Name a defining feature of pyoderma gangrenosum
purple overhanging edge
Which skin change is seen in grave’s disease?
pre-tibial myxoedema
List two skin manifestations observed in crohn’s disease
perianal ulcers and fistulae
erythema nodosum
pyoderma gangrenosum
List three skin manifestations associated with diabetes mellitus
ulcers
acanthosis nigricans
candida
granuloma annulare
List four dermatological manifestations of liver disease
palmar erythema spider naevi gynaecomastia jaundice bruising excoriations loss of secondary sexual hair
Which cancer is erythema gyratum associated with?
lung cancer
What is the main association of necrolytic migratory erythema?
islet cell tumour of pancreas
What skin signs may appear as a result of internal malignancy?
necrolytic migratory erythema, erythema gyratum repens, acanthosis nigricans
What is a skin feature of hypothyroidism?
dry skin
What are features exclusive to diabetes that affect the skin?
necrobiosis lipoidica, diabetic dermopathy, scleredema, leg ulcers, granuloma annulare
