Eczema Flashcards
List three triggers for eczema
fragrance, sweat, pollen, animals, dust mite, changes in temp, food, damp/mould
Does eczema affect flexures or extensors?
flezures- knees and elbows
What is the management of eczema?
Emollients, topical steroids, antihistamines, bandages, avoidance of exacerbation factors, soap substitutes
Name a mild steroid cream
hydrocortisone
betnovate= potent
What is the histological description of eczema?
spongiotic reaction pattern- space between epidermal keratinocytes, and increase in fluid between epidermal cells
Which cells are increased in eczema?
eosinophils
In eczema there is an inherited barrier defect. What does this mean?
genetically inherited ‘barrier defect’, leading to increased permeability and reduces its antimicrobial function
Expression of which protein is thought to cause dysfunction in barrier integrity?
Filaggrin, which is a protein that binds to keratin fibres in the epidermal cells
Eczema/dermatitis can be divided into endogenous and exogenous. Name two examples of endogenous causes.
atopic, seborrhoeic, discoid, varicose, pompholyx
Name two types of exogenous causes of dermatitis
contact (allergic, irritant), photoreaction (allergy, drug)
What are complications of atopic eczema?
staph infection, viral infection, tiredness, growth reduction, psychological impact
Which viruses are people with eczema at risk of?
molluscum, viral warts, eczema herpeticum
What are common triggers for contact dermatitis?
- nickel-jewellery, coins 2. Chromate- cement 3. Cobalt- pigment 4. Fragrance
Name three types of dermatitis
- Atopic=eczema 2. Contact dermatitis 3. Seborrhoeic dermatitis 4. Venous dermatitis
In which condition can serborrhoeic dermatitis be supportive diagnostically?
HIV, if unresponsive to treatment then test for HIV
