Skin infections (viral, fungi & mite) Flashcards
What does HSV stand for?
Herpes simplex virus !
What are the eight variants of human herpes viruses and what kind of viruses are they (DNA or RNA?)
HHV 1 - HSV type 1 HHV 2 - HSV type 2 HHV 3 - VZV HHV 4 - EBV HHV 5 - CMV HHV 6 - Roseola virus HHV 7 - HHV 7 (same name) HHV 8 - Kaposi Sarcoma
DNA VIRUSES
Which cells do HSV type 1, 2 and varicella zoster virus target?
Mucoepithelial cells
Which two HHVs target lymphocytes and what are the other names for these viruses?
HHV 6 and HHV 8
HHV 6 - Roseola virus
HHV 8 - Kaposi Sarcoma
Which HHV targets B cells and what is its name?
EBV (HHV 4)
Which HHV targets T cells and what disease does it cause?
HHV 7 - causes Piryriasis rosea
Which HHV targets monocytes and epithelial cells and what diseases does it cause?
HHV 5 - CMV
Infectious mononucleosis like syndrome
Retinitis
What is the is the site of latency of EBV and KS?
B cells
What is the site of latency for CMV, roseola and HHV7?
Lymphocytes
What is the site of latency for HSV 1, 2 and VZV?
Neuron
What disease do HSV 1 and 2 cause?
Type 1 - oral herpes
Type 2 - genital herpes
What are the clinical presentations of type 1 and 2 herpes simplex viruses?
Vesicular rash (2w)
Eczema herpeticum
Herpes encephalitis
What do you call the first presentation of type 1 herpes and what does it look like?
Stomatitis - inflamed, reddish lips
How do you diagnose herpes simplex?
Take a swab and do PCR
What is the treatment for herpes simplex?
Acyclovir
What are the symptoms of varicella zoster virus?
Malaise
Fever
Sore throat
Vesicular rash
Where do the rashes concentrate in varicella?
Face - esp in mouth
Necks
Trunk
What can chicken pox cause in older people??
Pneumonia
Coma
Blindness
Chronic facial pain